May 21, 2009
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Almonds may help to improve immune function

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PHILADELPHIA – Almond skins may be associated with benefits to the immune system, according to results of a new study presented at the 109th General Meeting of the American Society for Microbiology, held here this week.

Findings from a study conducted in the United Kingdom and Italy indicated that almond skins may improve the immune surveillance of peripheral blood mononuclear cells toward viral infection. The mechanism to do so may involve triggering helper T 1 cells and stimulating helper T 2 cells, according to the findings. The researchers said this “could represent a new strategy” toward the balance between helper T 1 cells and helper T 2 cells.

The researchers examined natural and blanched almond skins. These skins were subjected to a physical and biochemical simulator of the gastrointestinal tract. Cytotoxic concentrations were used: 60 μg/mL for the skin and 10 μl for the digesta. These skins were then tested with two types of peripheral blood mononuclear cells: some that were infected with herpes simplex virus-2 and some that were not.

The results indicated a significant decrease in herpes simplex virus-2 replication and a high production of pro-inflammatory cytokines in the natural almond skins. The blanched almond skins were not associated with the same reduction of replication of herpes simplex virus-2.

The researchers said the results indicate that almond skins may have a beneficial effect on fighting infections and may also offer benefits related to the treatment of chronic diseases.

For more information:

  • Mandalari G. E-047. Presented at: The 109th General Meeting of the American Society for Microbiology. May 17-21, 2009. Philadelphia.