Steatohepatitis/Metabolic Liver Disease News

Lipocine completed patient enrollment in a proof-of-concept clinical study of LPCN 1144 for the treatment of nonalcoholic steatohepatitis, according to a press release.

Longer lactation duration lowered the odds for developing nonalcoholic fatty liver disease in midlife among nursing women, according to a study recently published in Journal of Hepatology.

Adverse metabolic conditions showed a greater impact on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, significant fibrosis, kidney dysfunction and atherogenic profile compared with “healthy” obesity, according to a recently published study.

Results from a recent study showed that current smoking habits and length of time smoking correlated with an increased risk for nonalcoholic fatty liver disease in both men and women.

Interim analysis results from a phase 2b trial of MSDC-062K for patients with nonalcoholic steatohepatitis and fibrosis showed significant improvements in liver function and insulin resistance at 6 months compared with baseline, according to a press release from Cirius Therapeutics.

Results from a phase 2 trial of JKB-122 for treating nonalcoholic fatty liver disease demonstrated significant improvement on diagnosis and biomarkers after 12 weeks, according to a press release from TaiwanJ Pharmaceuticals.

This year at the American College of Gastroenterology Annual Meeting, several hepatology specialists discussed the changing landscape of liver disease health care, such as increasing rates of nonalcoholic fatty liver disease which is quickly becoming the number one indication for liver transplantation.

Several recent studies have shown that nonalcoholic fatty liver disease and nonalcoholic steatohepatitis rates are increasing steadily in the U.S. and other countries following increased trends for obesity. NAFLD and NAFLD-related complications such as liver cancer are also becoming more common indications for liver transplantation.

PHILADELPHIA — FibroScan screening for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis could significantly improve patient diagnosis and care, as data presented at the American College of Gastroenterology Annual Meeting showed that FibroScan found a significant number of undiagnosed cases.

PHILADELPHIA — Malnutrition as measured by subjective global assessment correlated significantly with decreased health-related quality of life in patients with cirrhosis, according to research presented at the American College of Gastroenterology Annual Meeting.