Steatohepatitis/Metabolic Liver Disease News

Echosens announced a pilot study in collaboration with the NASH Network designed to appropriately identify patients with progressive nonalcoholic fatty liver disease using FibroScan, according to a press release.

Nonalcoholic fatty liver disease is an independent risk factor for diabetes development in adults without obesity, according to findings published in Nutrition, Metabolism and Cardiovascular Diseases.

Results from the STELLAR-4 phase 3 study showed that selonsertib did not meet the pre-specified 48-week endpoint of histologic improvement by 1 or more stage in fibrosis without worsening of nonalcoholic steatohepatitis, according to a press release.

Propensity to store fat intra-abdominally varies significantly by ethnicity and race, with higher rates seen in Japanese Americans and lower rates seen in African Americans compared with other groups, according to data published in Gastroenterology.

EASL announced the formation and official launch of MICROB-PREDICT, a project designed to research the human microbiome for clinical research and therapeutic development in the field of decompensated cirrhosis and acute-on-chronic liver failure, according to a press release.

Among the three largest Hispanic population subgroups, researchers found high levels of heterogeneity in chronic liver disease-related mortality patterns, according to a recently published study.

Researchers validated the disease-specific Chronic Liver Disease Questionnaire for nonalcoholic steatohepatitis, also known as CLDQ-NASH, as a useful health-related quality of life instrument for patients with NASH.

The presence of lobular inflammation in patients with nonalcoholic fatty liver disease correlated with a lower health-related quality of life, along with sex and diabetes, according to a recently published study.

An 8-week diet low in free sugar content significantly improved hepatic steatosis among adolescent boys with nonalcoholic fatty liver disease compared with their usual diet, according to a study published in JAMA.

by Michael Charlton, MD