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Steatohepatitis/Metabolic Liver Disease News
Survodutide upholds ‘promising’ reduced liver fat, fibrosis biomarkers in MASH at 28 weeks
WASHINGTON — Survodutide sustained improvement in liver fat content, liver enzymes and fibrosis biomarkers in patients with metabolic dysfunction-associated steatohepatitis at 28 weeks, according to a late-breaking abstract presented here.
Prevalence of advanced fibrosis similar in lean, non-lean MASLD, linked to genetic risk
WASHINGTON — The risk for advanced fibrosis was similar among patients with lean and non-lean metabolic dysfunction-associated steatotic liver disease and may be associated with genetic risk, according to data at Digestive Disease Week.
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Larsucosterol rebounds to snag FDA breakthrough status for alcohol-related hepatitis
The FDA has granted breakthrough therapy designation to Durect’s larsucosterol for the treatment of patients with severe alcohol-associated hepatitis, despite mixed results from previously released topline data.
Parental obesity linked to up to 55% increased risk for MASLD among adult offspring
WASHINGTON — Parental obesity was associated with a nearly threefold increased risk for metabolic dysfunction-associated steatotic liver disease among offspring in early adulthood, according to data presented at Digestive Disease Week.
Bariatric surgery associated with lower mortality, health care cost in patients with MASLD
WASHINGTON — Bariatric surgery was associated with improved clinical outcomes and more cost-effective health care resource utilization among patients with metabolic dysfunction-associated steatotic liver disease, according to data.
‘Encouraging’ data: GLP-1RAs linked to lower risk for cirrhosis in MASLD, type 2 diabetes
WASHINGTON — Glucagon-like peptide-1 receptor agonists were associated with lower risk for progression to cirrhosis and hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease and type 2 diabetes.
GLP-1RA use in MAFLD, obesity lowers mortality, ‘provides cardiovascular benefits’
WASHINGTON — Patients with obesity and metabolic dysfunction-associated fatty liver disease taking glucagon-like peptide-1 receptor agonists had lower risk for all-cause mortality and major cardiovascular events, according to a presenter.
Playing sports may lower insulin resistance, reduce odds for MASLD in type 1 diabetes
Adults with type 1 diabetes who play sports have less insulin resistance and are less likely to develop metabolic dysfunction-associated steatotic liver disease, according to study findings.
Health care professionals ‘thrilled’ with approval of first treatment for MASH
An analysis of the global online conversations of more than 1,600 healthcare professionals has revealed celebration at news of the approval of the first treatment for adults with metabolic dysfunction-associated steatohepatitis.
Food insecurity boosts fibrosis odds in HIV with diabetes, lowers MASLD odds in HIV alone
Food insecurity was associated with lower odds of metabolic dysfunction-associated steatotic liver disease among patients with HIV, although the presence of diabetes increased the odds of fibrosis in this population, according to data.
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Headline News
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Headline News
Rise in alcohol use during pandemic endures as 'an alarming public health issue'
November 14, 20242 min read -
Headline News
AI identified patient messages sent by proxies, but also broke confidentiality
November 14, 20242 min read -
Headline News
Diabetes inequities persist worldwide, especially for low-, middle-income countries
November 14, 20243 min read