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Steatohepatitis/Metabolic Liver Disease News
The race is on for medical treatment of NASH
Nonalcoholic steatohepatitis is the second leading indication for liver transplantation in the United States but there are currently no FDA-approved treatments available.
NASH: A pandemic with an unmet need for pharmacotherapies
There is a significant medical need to find effective pharmacotherapies to manage NASH, the liver disease that is really a pandemic.
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Ideal CV health behaviors tied to lower odds of NAFLD
Ideal CV health behaviors were associated with lower nonalcoholic fatty liver disease, or NAFLD, prevalence among participants in the Multi-Ethnic Study of Atherosclerosis cohort.
Poxel announces plans for phase 2b trial of AMPK activator for NASH
Poxel announced additional positive phase 2a results and plans for a phase 2b trial of PXL770, an oral direct adenosine monophosphate-activated protein kinase activator intended for nonalcoholic steatohepatitis.
Many drug therapy options exist for NAFLD
Lipid-lowering therapies, diabetes drugs and liver-related therapies are among the medication options for patients with nonalcoholic fatty liver disease, according to a presentation at the National Lipid Association Scientific Sessions.
NASH drug helps reduce liver fat with good tolerability
Patients with non-alcoholic steatohepatitis treated with BIO89-100 experienced clinically meaningful reduction in liver fat, according to research presented at The Liver Meeting Digital Experience.
Semaglutide produces NASH resolution without worsening fibrosis
Patients treated with subcutaneous semaglutide experienced better resolution of non-alcoholic steatohepatitis without worsening fibrosis, according to the results of a placebo-controlled study presented at The Liver Meeting Digital Experience.
Malnutrition linked with increased mortality, infections in alcoholic hepatitis
Malnutrition correlated with increased hospital mortality and infections in patients with alcoholic hepatitis, according to a presenter at The Liver Meeting Digital Experience.
Tropifexor safe up to 48 weeks for NASH
New data showed favorable safety measures up to 48 weeks of treatment with tropifexor in nonalcoholic steatohepatitis, according to a presenter at The Liver Meeting Digital Experience.
Combination therapies impact NAFLD more than singular therapy
Combining therapies with different mechanisms of action to treat non-alcoholic fatty liver disease resulted in greater reduction in liver-related measures, according to a presenter at The Liver Meeting Digital Experience.
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Headline News
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