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Steatohepatitis/Metabolic Liver Disease News
Nonalcoholic fatty liver disease linked to increased risk for dementia
Patients with nonalcoholic fatty liver disease had an increased risk for dementia, with stronger risk existing for those with comorbid heart disease or stroke, according to a study published in Neurology.
VIDEO: Terns Pharma ‘builds upon pipeline’ of NASH, obesity research
In a Healio video exclusive, Diana Chung, chief development officer at Terns Pharmaceuticals, highlights data on TERN-501, a thyroid hormone receptor beta-agonist for patients with nonalcoholic steatohepatitis.
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Fatigue linked to worse clinical prognosis, quality of life in patients with NAFLD
LONDON — Lower fatigue scores at baseline correlated with adverse clinical events among patients with advanced nonalcoholic steatohepatitis, according to research presented at the International Liver Congress.
Resmetirom ‘has potential to be first medication approved’ for patients with NASH
LONDON — Resmetirom was safe and well tolerated at 100 mg and 80 mg doses in patients with nonalcoholic steatohepatitis, according to late-breaking research presented at the International Liver Congress.
MRE plus FIB-4 bests MAST, FAST to ‘rule in or rule out’ stage 2 fibrosis in NAFLD
LONDON — Magnetic resonance elastography in combination with the fibrosis-4 index was a better predictor of significant fibrosis in patients with nonalcoholic fatty liver disease vs. other noninvasive techniques, noted a presenter here.
Support vector machines lead machine learning models in predicting liver decompensation
LONDON — Support vector machines had the highest accuracy in predicting liver decompensation among a subset of patients in Germany compared with other machine learning models, according to data presented at the International Liver Congress.
NAFLD, alcohol-associated liver disease spur rise in global liver cancer deaths
LONDON — Nonalcoholic fatty liver disease and alcohol-associated liver disease are among the main contributors of increased mortality related to chronic liver disease and liver cancer burden, according to research.
Liver fibrosis linked to CV events, survival in NAFLD, chronic kidney disease
LONDON — Elevated noninvasive markers of liver fibrosis correlated with an increased risk for cardiovascular events, end-stage renal disease and worse survival in patients with chronic kidney disease and nonalcoholic fatty liver disease.
Health-related quality of life worse in NAFLD patients compared with general population
LONDON — Patients with nonalcoholic fatty liver disease had worse health-related quality of life, regardless of fibrosis stage, compared with the general population, according to research presented at the International Liver Congress.
Younger-onset type 2 diabetes increases risk for liver-related events
LONDON — Younger-onset type 2 diabetes increased the risk for liver-related events among patients with nonalcoholic fatty liver disease, according to research presented at the International Liver Congress.
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