Steatohepatitis/Metabolic Liver Disease News

A patient outcomes simulator found that non-liver-related mortality could surpass liver-related mortality in patients with nonalcoholic fatty liver disease, depending on age and fibrosis stage at diagnosis, noted data in JAMA Network Open.

Higher state-level geographic density of gastroenterologists was linked with decreased mortality from alcohol-associated liver disease in adults aged 25 years or older, according to new data in Clinical Gastroenterology and Hepatology.

Despite global declines in liver cancer mortality attributed to hepatitis B and C, liver cancer mortality rose sharply in the Americas, driven by an increase in nonalcoholic steatohepatitis, according to data published in Cell Metabolism.

In one of the largest exome-sequencing studies on liver health, researchers found rare genetic loss-of-function variants in the CIDEB gene were associated with significant protection from liver damage and disease.

Gastroenterologists and hepatologists were leaders in nonalcoholic steatohepatitis diagnosis and viewed as primary coordinators of care, but the condition is still underdiagnosed and undertreated overall, noted data in BMC Gastroenterology.

A noninvasive liquid biopsy test diagnosed the presence and severity of nonalcoholic steatohepatitis and liver fibrosis more reliably than liver biopsy, according to research published in Gut.

Healio handpicked its top stories on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, which highlight risks for children with NAFLD, how fatigue relates to quality of life, treatment with resmetirom and more.

LONDON — Longitudinal serum alanine aminotransferase trajectories remained stable over time among a subset of patients with nonalcoholic fatty liver disease, according to research presented at the International Liver Congress.

Prenatal exposure to endocrine-disrupting chemicals may be a cause of increased incidence of nonalcoholic fatty liver disease in children, according to a study published in JAMA Network Open.

Researchers reported an increased risk for type 2 diabetes in children with nonalcoholic fatty liver disease, highlighting the need for targeted prevention and screening, according to a study in Clinical Gastroenterology and Hepatology.