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Oncology News
Nucleos(t)ide analogue reduces risk for liver cancer in HBV
Recently published data showed an association between nucleos(t)ide analogue therapy for chronic hepatitis B virus and a reduced risk for intrahepatic cholangiocarcinoma.
Liver transplant, cancer stage increase HCC care costs, survival time
A recently published analysis of veterans with hepatocellular carcinoma showed that receipt of liver transplantation, Barcelona Clinic Liver Cancer stage and multidisciplinary tumor board correlated with higher 3-year health care costs but increased survival time.
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Liver cancer risk factors more prevalent among Mexicans living in US
Mexican-American individuals residing in the United States had more risk factors for liver cancer than their counterparts living in Mexico, according to study results presented at American Association for Cancer Research Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved.
Muscle volume loss correlated with increased mortality in cirrhosis
Among patients with cirrhosis, muscle volume loss and hepatocellular carcinoma within Milan criteria were prognostic factors for mortality, according to recently published data.
FDA approves Opdivo for previously treated hepatocellular carcinoma
The FDA approved nivolumab for the treatment of patients with hepatocellular carcinoma who underwent prior therapy with sorafenib.
Reduced Nexavar dosage yields cost benefits, does not affect OS in HCC
Patients with hepatocellular carcinoma who started Nexavar therapy at reduced dosages had a lower total cumulative pill cost and were less likely to discontinue due to adverse effects, according to recently published data. Additionally, lower starting doses did not affect overall survival.
Gallbladder cancer linked to mold toxin
Dietary exposure to aflatoxin, or toxins produced by fungi affecting certain crops, may increase the risk for gallbladder cancer, according to new research.
HCC rates vary by race in US, highest among Asian-Pacific Islanders
Among U.S. veterans with hepatitis B, researchers found that the risk for hepatocellular carcinoma was higher among Asian-Pacific Islanders than Caucasians and African-Americans, increased with the presence of cirrhosis, and significantly increased among those without cirrhosis after age 40 regardless of race.
Higher FIB-4 index in patients with HBV linked to increased HCC risk
In a cohort of patients with chronic hepatitis B without cirrhosis, the risk for hepatocellular carcinoma was significantly higher among those with a FIB-4 index over 1.29, according to recently published data.
Two liver cancer T-cell therapies receive orphan drug designation
The FDA recently granted two orphan drug designations to Lion TCR for T-cell therapy products for the treatment of hepatocellular carcinoma, according to a press release.
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