Oncology News

WASHINGTON — In this exclusive video perspective from Digestive Disease Week 2018, John B. Kisiel, MD, a gastroenterologist from the Mayo Clinic in Rochester, Minn., shares results of a study in which plasma assay of methylated DNA markers detected hepatocellular carcinoma across all stages.

WASHINGTON — In this exclusive video perspective from Digestive Disease Week 2018, Steven L. Flamm, MD, chief of the Liver Program at Northwestern University Feinberg School of Medicine in Illinois, reviews some of the important clinical presentations in liver disease from the meeting.

CHICAGO — Adjuvant FOLFIRINOX chemotherapy improved OS and PFS compared with gemcitabine among patients with surgically removed nonmetastatic pancreatic ductal adenocarcinoma, according to data from the phase 3 PRODIGE 24/CCTG PA.6 trial presented at ASCO Annual Meeting.

Fibrolamellar hepatocellular carcinoma, a rare childhood liver cancer, metastasized to the brain, prompting researchers to recommend surveillance neuroimaging for patients with advanced disease, according to published findings.

Exelixis announced that the FDA accepted a supplemental new drug application for Cabometyx tablets as a treatment for patients with previously treated advanced hepatocellular carcinoma, according to a press release.

Patients with hepatitis B-related decompensated cirrhosis who achieved virologic response after treatment with either Baraclude or Epivir had significantly improved long-term and transplant-free survival, according to results of a 10-year observational study.

Overweight and obesity appeared associated with an increased risk for 12 cancer types, according to World Cancer Research Fund’s new report.

Results of two phase 3 trials showed that Doptelet significantly reduced the need for platelet transfusions or rescue procedures for bleeding compared with placebo in patients with thrombocytopenia and chronic liver disease who underwent a scheduled procedure.

The FDA approved avatrombopag to treat low blood platelet count among adults with chronic liver disease who are scheduled to undergo a medical or dental procedure.

Residents of Japan with higher concentrations of vitamin D were less likely to develop cancer than those with lower levels, according to a cohort study recently published in The BMJ.