Oncology News

In contrast to current reports that show liver cancer rates increasing on the global scale, the incidence of hepatocellular carcinoma remained stable for 18 years in a large German cohort study.

Diet and lifestyle are tied closely with liver health both as risk factors for complications such as nonalcoholic fatty liver disease and as the best intervention in the case of fatty liver development and progression.

Innovent Biologics announced first patient dosing in a phase 2/3 trial of Tyvyt with IBI305 for patients with advanced hepatocellular carcinoma taking place in China, according to a press release.

Mundipharma EDO and Imbrium Therapeutics announced that the FDA granted orphan drug designation to etoposide toniribate for the treatment of cholangiocarcinoma, according to a press release.

HIV seropositivity appeared associated with shorter OS among patients with hepatocellular carcinoma despite sufficient antiretroviral treatment, according to results of a global multicohort study published in Journal of Clinical Oncology.

Increased intake of whole grains correlated with a reduced risk for hepatocellular carcinoma among adults regardless of cancer etiology, according to study results published in JAMA Oncology.

The addition of pembrolizumab to best supportive care failed to extend survival among patients with advanced hepatocellular carcinoma who received prior systemic therapy, according to study results released by the agent’s manufacturer.

Between 2003 and 2016, liver graft loss and mortality rates among recipients of grafts from older donors improved; however, discard rates of older donor grafts continued to increase and use of older donor grafts decreased, according to a study published in JAMA Surgery.

Results of a prospective study showed that treatment with direct-acting antivirals for hepatitis C correlated with significantly reduced risks for hepatocellular carcinoma and mortality, according to a study published in The Lancet.

Among the three largest Hispanic population subgroups, researchers found high levels of heterogeneity in chronic liver disease-related mortality patterns, according to a recently published study.