Oncology News

A novel armored chimeric antigen receptor T-cell therapy targeting the glypican-3 protein showed antitumor activity among children with advanced liver cancer, according to preliminary results of a phase 1 trial presented at the virtual American Society of Gene and Cell Therapy Annual Meeting.

Regular use of aspirin appeared to reduce the risk for several digestive tract cancers, according to results of a meta-analysis published in Annals of Oncology.

Atezolizumab in combination with bevacizumab improved OS and PFS compared with sorafenib among patients with unresectable hepatocellular carcinoma, according to results of the randomized phase 3 IMbrave150 study published in The New England Journal of Medicine.

The FDA granted orphan drug designation to MIV-818 for the treatment of hepatocellular carcinoma.

The FDA granted accelerated approval to pemigatinib for treatment of certain adults with previously treated unresectable cholangiocarcinoma.

Primary liver cancer rates continue to increase in many regions of the world despite extensive efforts to prevent the disease, according to study results published in Cancer.

Low-dose aspirin use appeared associated with significantly lower risk for hepatocellular carcinoma and lower liver-related mortality among patients with chronic viral hepatitis, according to results of a retrospective study published in The New England Journal of Medicine.

The FDA granted accelerated approval to nivolumab plus ipilimumab for treatment of patients with hepatocellular carcinoma who previously received sorafenib.

The FDA granted breakthrough device designation to the Elecsys GALAD score to support earlier diagnosis of hepatocellular carcinoma.

The National Cancer Institute awarded a Cedars-Sinai team $9.1 million by to study how cancer metastasizes to the liver and finding ways to block it. Consisting of four parts, the study’s main focus will be the interaction between dietary fat and fatty liver disease as well as the mechanisms that allow for the spread, according to a press release.