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Oncology News
Black patients with HCC have worse overall survival
Black patients with hepatocellular carcinoma have worse overall survival compared with white patients, according to study results.
Black patients less likely to undergo treatment for colorectal liver metastases
Black patients with colorectal liver metastases had a lower likelihood of undergoing chemotherapy or resection and shorter survival than their counterparts of other races and ethnicities, according to a research letter in JAMA Network Open.
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Women more likely to have noncirrhotic HCC, underlying NAFLD
Compared with men, women had a significantly higher frequency of underlying nonalcoholic fatty liver disease and noncirrhotic hepatocellular carcinoma, according to data published in the American Journal of Gastroenterology.
Chronic liver diseases associated with COVID-19 mortality
Chronic liver diseases, including decompensated cirrhosis and hepatocellular carcinoma, were associated with increased mortality in patients with COVID-19, according to study results.
Stivarga, Opdivo have similar survival outcomes in HCC
Among patients with hepatocellular carcinoma who first failed Retevmo, Stivarga and Opdivo provided similar outcomes in terms of survival as second-line treatments, according to research presented at The Digital International Liver Congress.
Dabrafenib-trametinib combination active in BRAF-mutated biliary tract cancer
The combination of dabrafenib and trametinib appeared active among patients with BRAF V600E-mutated biliary tract cancer, according to results of an ongoing phase 2 basket trial published in The Lancet Oncology.
Novel tremelimumab-durvalumab regimen safe, effective in advanced liver cancer
A single 300 mg priming dose of tremelimumab in combination with durvalumab appeared safe and active among patients with advanced hepatocellular carcinoma, according to study results presented during the ASCO20 Virtual Scientific Program.
Donafenib extends OS in advanced liver cancer
Donafenib conferred a modest but statistically significant OS improvement as first-line therapy for advanced hepatocellular carcinoma, according to study results presented during the ASCO20 Virtual Scientific Program.
FDA approves immunotherapy regimen for advanced liver cancer
The FDA approved atezolizumab in combination with bevacizumab for the treatment of patients with unresectable or metastatic hepatocellular carcinoma who have not received prior systemic therapy.
Be aware of all factors related to HCC risk, not just HCV
Hepatitis C virus infection remains a strong driver of hepatocellular carcinoma with a high rate of progression to cirrhosis over an extended follow-up period, according to a study in International Journal of Molecular Sciences.
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