Liver Injury/Regeneration News

Patients with acute-on-chronic liver failure with an improved model for end-stage liver disease score more than 2 weeks after disease onset had a decreased risk for mortality after 60 days, according to study data.

Liver disease is the third most common cause of premature death in the United Kingdom, with mortality rates increasing by 400% since 1970. In a new report, Roger Williams, MD, director of the Institute of Hepatology in London, and colleagues provide recommendations for improving the standard of care for patients with liver disease in hospitals and create quality preventive measures for people with excessive alcohol use and obesity to reduce the mortality rate and burden of the disease.

Variants of the CYP2C9 gene were associated with bosentan-induced liver injury among patients with pulmonary hypertension undergoing therapy with bosentan, according to study data.

BOSTON – Jasmohan S. Bajaj, MD, associate professor of gastroenterology, hepatology and nutrition at Virginia Commonwealth University and Hunter Holmes McGuire VA Medical Center, discussed his presentation on acute on chronic liver failure during an emerging trends symposium at The Liver Meeting.

PHILADELPHIA — Antimicrobials and herbal and dietary supplements are the most common causes of idiosyncratic drug-induced liver injury, or DILI, according to data presented at the ACG Annual Scientific Meeting.

PHILADELPHIA — Due to its nature, idiosyncratic drug-induced liver injury is a diagnosis of exclusion, making it elusive and clinically challenging.

PHILADELPHIA —Liver transplant recipients with intra-abdominal infections who develop liver abscesses after transplantation had an increased risk for mortality and possible re-transplantation, according to data presented at IDWeek 2014.

New study data show that obesity is strongly correlated with an advanced epigenetic age of liver tissue.

Organovo Holdings’ exVive3D Human Liver Model was named a finalist in the Diagnostics & Research Tools category for Connect’s 2014 Most Innovative New Product Awards, according to a company press release.

Tonsil-derived mesenchymal stem cells, used in combination with a heating solution, produced a 3D growth factor system designed to repair liver damage without surgery in a recent study.