Liver Injury/Regeneration News

In patients treated with preoperative chemotherapy prior to resection for colorectal liver metastases, sinusoidal dilation and nodular regenerative hyperplasia did not regress until 9 months post-chemotherapy, while steatosis and steatohepatitis persisted even longer, according to a recent study.

Patients with severe alcoholic hepatitis who were homozygous for the rs738409:G variant in the PNPLA3 gene have an increased risk for mortality even when they stop drinking alcohol, according to recently published data.

Data from the Veterans Aging Cohort Study showed an association between higher FIB-4 scores and increased risk for congestive heart failure, including patients with moderate liver fibrosis.

Recently published studies have shown new innovations for measuring liver stiffness, such as a novel Doppler imaging technology and an analysis of magnetic resonance elastography for measuring liver stiffness in pediatric patients.

After 12 weeks of exercise without weight change or reduction of alcohol, patients with obesity who consume alcohol increased lean body mass, reduced fat mass and reduced cytokeratin-18, but no effect on liver lipid was seen, according to results of a recently published study.

Recently published data showed that Japan Hepatic Encephalopathy Prediction Model, or JHEPM, probability and prothrombin-time international ratio values can be used as predictive measures for the progression from acute liver injury to acute liver failure.

CHICAGO — According to a presentation at Digestive Disease Week, modest alcohol consumption of half to one drink of alcohol per day showed an increase in survival rates in patients with non-alcoholic fatty liver disease, while more than one and a half drinks per day was linked to an increased trend in harm.

CHICAGO — Bariatric surgery increases the risk of subsequent acute liver injury, according to results of a study presented at Digestive Disease Week.

AMSTERDAM — At this year’s International Liver Congress, EASL presented new clinical practice guidelines for the diagnosis, management and treatment of hepatitis B, primary biliary cholangitis, primary sclerosing cholangitis, alcoholic liver disease and acute liver failure.

AMSTERDAM — EASL presented its new Clinical Practice Guideline addressing the management of alcoholic liver disease at the International Liver Congress.