Liver Injury/Regeneration News

Chewing khat leaves correlated with an increased risk for chronic liver disease, according to results of a case-controlled hospital-based study. The data further showed the association was dose-dependent among men.

Alcohol consumption in young men was associated with an increased, dose-dependent risk for severe liver disease up to 39 years later in life, according to results of a recently published study.

Anabolic steroids were the most common cause of drug-induced liver injury among patients with heavy alcohol consumption, according to a recently published study. However, heavy alcohol consumption did not correlate with worse outcomes compared with nondrinkers.

Analysis of the Spanish Drug-Induced Liver Injury registry showed that cases of herbal and dietary supplement-induced liver injury were more common in young women than older patients or men and correlated with hepatocellular injury and high levels of transaminases.

Acetaminophen-induced acute liver injury and failure are more common in women than men, according to recently published data. Women also have greater critical care needs and have an increased risk for severe hepatic encephalopathy, potentially related to increased use of sedatives.

A recent trial of extracorporeal cellular therapy for severe alcoholic hepatitis did not achieve its primary or secondary endpoints of increased survival compared with standard of care, but did verify that high creatinine and international normalized ratio among those who received the treatment predicted negative outcomes.

Three existing prognostic scoring systems evaluated in the Steroids or Pentoxifylline for Alcoholic Hepatitis trial, or STOPAH, demonstrated improved identification of poor prognosis in patients with alcoholic hepatitis over the commonly used Discriminant Function.

After completing a safety review of green tea extract in natural health products, Health Canada is strengthening warnings on labels of these products to avoid the risk for liver injury, according to a press release.

WASHINGTON — Mislabeling or omission of ingredients occurs frequently in herbal and dietary supplements, especially among bodybuilding and weight loss products, according to a presentation at The Liver Meeting 2017.

WASHINGTON — Beginning Friday, October 20, Healio Gastroenterology and Liver Disease will provide live coverage from the The Liver Meeting 2017.