Liver Injury/Regeneration News

PHILADELPHIA – Patients who received treatment with multiple immunotherapy drugs had increased risks for drug-induced liver injury compared with single therapy courses, as presented at the American College of Gastroenterology Annual Meeting.

BioIVT announced results of their research into cholestatic drug-induced liver injury and the BSEP bile acid transporter, according to a press release.

Studies that focus on specific patient characteristics and demographics often reveal key strategies to improve health care at the individual patient level. Liver disease research focused on women and mothers has shown that women face fertility risks with hepatitis C and higher risks for liver injury or failure with chronic liver disease.

Researchers established new blood-based biomarker reference intervals to assess drug-induced liver injury and recovery, according to a recently published study.

Corticosteroid therapy reduced mortality risk within 28 days of treatment among patients with severe alcoholic hepatitis compared with pentoxifylline or placebo, although the effect did not remain in the following 6 months, according to a recently published meta-analysis.

PARIS — Alcohol abstinence did not reduce the risk for hepatocellular carcinoma among patients with Child-Pugh class A or B alcohol-related cirrhosis, according to a presentation at the International Liver Congress 2018.

PARIS — Beginning Wednesday, April 11, Healio Gastroenterology and Liver Disease will provide live coverage from the International Liver Congress 2018.

Chronic liver damage known as cirrhosis has a variety of causes. What remains constant is its potential progression to liver failure. Researchers continue to seek verifiable methods to prevent the development of cirrhosis firstly and, secondly, to predict its progression or involvement to worse conditions such as liver cancer, coronary artery disease or hepatic encephalopathy.

The FDA has added a new boxed warning to Ocaliva, a treatment for primary biliary cholangitis, to clarify current recommendations, according to a release from the agency. The FDA will also require a medication guide for patients, as incorrect dosage can lead to liver injury.

Dual hypothermic oxygenated machine perfusion, or DHOPE, reduced ischemia-reperfusion injury of bile ducts after transplantation with donation after circulatory death livers, according to a recently published study.