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Hepatitis C News
Alcohol use disorder compromises benefits of DAA therapy for HCV
An international study showed that alcohol use disorder contributed significantly to liver disease burden in patients with hepatitis C. Researchers suggest that, where appropriate, countries develop strategies that combine direct-acting antiviral therapy with management of alcohol use disorders.
ID specialists search for ways to reach homeless
People who are homeless are more vulnerable to many infectious diseases than the general population and harder to reach for treatment.
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Recent injection drug users achieve high adherence, SVR during HCV therapy
Most patients with hepatitis C who were recent injection drug users achieved sustained virologic response after treatment with direct-acting antiviral Epclusa, according to recently published study results.
HCV hospitalizations increasing among baby boomers, men, drug users
Hospitalization for hepatitis C increased significantly between 2005 and 2014, especially among baby boomers, men, African-American and Hispanic patients, and patients with mental health and substance abuse disorders, according to data from a Healthcare Cost and Utilization Project statistical brief.
Advocacy organization launches call-to-action to eliminate HCV in Canada
The Canadian Treatment Action Council launched a call-to-action campaign to end hepatitis C in Canada, according to a white paper published by the organization. The authors focused on treatment access policy issues in Canada that must be addressed to achieve the WHO elimination targets by 2030.
Safe injection sites receive support in face of opioid epidemic
On Jan. 23, 2017, Philadelphia city officials announced their support for supervised drug injection sites to combat the ongoing opioid epidemic, which has led to increased rates of infectious disease transmissions such as hepatitis C and HIV.
Increases in acute HCV correlate with growing opioid epidemic in US
Results of a recent study showed a significant correlation between the increase of acute hepatitis C cases in the U.S. and the country’s current opioid epidemic. Acute HCV and admissions for opioid injection drug use increased significantly among individuals aged 18 years to 39 years, both men and women, and specific ethnicities.
Immunosuppression, cirrhosis decrease SVR rates in HIV/HCV coinfection
Direct-acting antiviral therapy was safe and highly effective in patients coinfected with HIV and hepatitis C, according to a recently published study. Factors that negatively affected sustained virologic response rates included HIV-related immunosuppression, HCV RNA load, severity of liver disease and suboptimal DAA-based regimens.
Top 5 stories about HCV
Hepatitis C virus continues to affect millions of people worldwide. WHO estimates that 71 million people are living with chronic HCV infection, and about 399,000 people die from complications of the virus each year, mostly from cirrhosis and hepatocellular carcinoma.
SVR for HCV with no advanced liver disease greatly reduces mortality risk
Patients with hepatitis C without advanced liver disease who achieved sustained virologic response with direct-acting antiviral therapy had significantly reduced all-cause mortality rates compared with both treated patients who did not achieve SVR and untreated patients, according to a recently published data.