Genetic Diseases News

Patients with nonalcoholic fatty liver disease who undergo bariatric surgery may experience DNA-altering effects that can reverse their disease symptoms, according to a recent study.

Patients who underwent liver transplantation to treat lethal genetic syndromes experienced high rates of survival, while factors such as age and preoperative life support increased mortality risk, in a recent study.

Variants in the PNPLA3, GCKR, TRIB1 and PPP1R3B genes are associated with histological factors of nonalcoholic fatty liver disease, according to data presented at the International Liver Congress in Amsterdam.

An association may exist between the presence of diabetes and severe liver fibrosis in patients with hereditary hemochromatosis, according to recent study results.

The FDA recently approved taliglucerase alfa for long-term enzyme replacement therapy to treat a form of the rare genetic disorder Gaucher’s disease, according to a press release.

After 3 months of treatment with bevacizumab, 80% of study participants with hereditary hemorrhagic telangiectasia had decreased cardiac output — of which 12% experienced normalization of cardiac output, according to data published in the Journal of the American Medical Association.

Nonalcoholic fatty liver disease was the most common cause of liver function test failure in a large prospective cohort study of primary care patients.

Non-alcoholic fatty liver disease was found in a study to not be associated with an increased risk of death.