Cirrhosis/Liver Failure News

Healio will present its sixth annual Disruptive Innovators Awards for gastroenterology and hepatology this fall.

Patients hospitalized with cirrhosis in low- or middle-income countries had significantly higher risk for mortality compared with patients in high-income countries, according to research in Lancet Gastroenterology & Hepatology.

The Global Liver Institute has marked June 8 as International NASH Day, part of a public education campaign to raise awareness and urgency about fatty liver disease and its advanced form, nonalcoholic steatohepatitis.

CHICAGO — In a Healio video exclusive, Sarah Khan, MD, explains that patients with advanced liver disease and concurrent fungal infection had worse acute-on-chronic liver failure and higher mortality than those with bacterial infection.

A U.S. District Court judge in Delaware has denied Norwich Pharmaceuticals’ motion to modify the court’s final judgment, which blocks the FDA from approving their 550 mg rifaximin generic until Oct. 2, 2029.

An FDA advisory committee voted against approval for obeticholic acid in pre-cirrhotic patients with liver fibrosis due to nonalcoholic steatohepatitis, citing “concerning” benefit-risk profile.

CHICAGO — Hispanic and Black patients with cirrhosis who developed COVID-19 infection had higher rates of mortality, as well as higher hospital charges of more than $340 million in 2020, according to a presenter at Digestive Disease Week.

CHICAGO — Patients readmitted to the hospital within 30 days for decompensated cirrhosis during the COVID-19 pandemic had fewer comorbidities but increased MELD-Na scores, according to data at Digestive Disease Week.

CHICAGO — Researchers reported a 262% increase in liver transplantation for acute-on-chronic liver failure in older patients from 2005 to 2021, with alcohol-related liver disease becoming the leading cause during the COVID-19 pandemic.

CHICAGO — Hospital admissions for alcohol-related cirrhosis jumped from March 2020 to March 2021, with associated increases in costs and mortality, according to study results presented at Digestive Disease Week.