Cirrhosis/Liver Failure News

Combination treatment with Olysio and Sovaldi was more effective in treating patients with hepatitis C-related Child’s Class A cirrhosis vs. treatment with pegylated interferon, ribavirin and Sovaldi, according to study data published in Gastroenterology.

Obeticholic acid effectively decreased alanine aminotransferase, gamma-glutamyl transpeptidase and alkaline phosphatase levels compared with placebo, in patients with primary biliary cirrhosis who failed previous therapy with ursodeoxycholic acid, according to data published in Gastroenterology.

High mottling score and knee tissue oxygen saturation accurately predicted mortality rates in patients with cirrhosis and septic shock, according to study data published in the Journal of Hepatology.

In a cohort of patients with hepatitis B virus infection-related acute–on-chronic liver failure, thyroid stimulation hormone level was a useful indicator for determining severity and prognosis, according to published data.

Subclasses of serum immunoglobulin G were distinct but varied across autoimmune disorders, according to recently published research.

SEATTLE — Many adults with hepatitis C virus born between 1945 and 1965 had severe fibrosis or cirrhosis, according to data presented at CROI 2015.

Intestinal lesions were prevalent in adolescents and young adults with cystic fibrosis and cirrhosis and associated with altered fecal microbiome and slower small bowel transit time, according to recently published data.

People of ethnic origin, mainly Hispanics, had an increased risk for alcoholic liver disease compared with Caucasians, according to new study data.

Patients with hepatorenal syndrome, or HRS, treated with a regimen of terlipressin/albumin had higher rates of improved renal function vs. patients treated with a regimen of midodrine and octreotide/albumin, according to newly published data in Hepatology.

Danish patients with chronic liver disease, especially those with liver cirrhosis, had an increased risk for mortality within 90 days after being hospitalized for peptic ulcer bleeding vs. patients without chronic liver disease, according to study data.