Cirrhosis/Liver Failure News

Kuvan was not more effective in reducing portal pressure in patients with cirrhosis and portal hypertension than placebo, according to new study data.

Intercept Pharmaceuticals, Inc. has submitted a new drug application to the FDA for obeticholic acid to be used in combination with ursodeoxycholic acid to treat primary biliary cirrhosis, according to a press release.

Low 25-hydroxyvitamin D3 levels were found to be associated with advanced liver disease, poor outcomes and infectious complications in patients with cirrhosis, according to study data.

Researchers in Korea used transient elastography and found it to be useful in identifying subclinical cirrhosis among patients at risk for hepatitis B virus infection-related hepatocellular carcinoma who did not have evidence of cirrhosis, according to study data.

Granulocyte colony-stimulating factor with darbopoietin alpha was effective in extending survival in patients with decompensated cirrhosis, according to study data.

Wisteria floribunda agglutinin-positive Mac-2-binding protein serum level was found to be an accurate biomarker in predicting liver fibrosis and determining prognosis of primary biliary cirrhosis, according to new data published in the American Journal of Gastroenterology.

In the Study of Acute Liver Transplantation trial, researchers found that paracetamol overdose was prevalent and an indicator for all-cause acute liver failure leading to registration on transplantation lists among various European countries, especially in Ireland and the United Kingdom, according to newly published data.

In a large cohort of hospitalized patients with cirrhosis, researchers found that inpatient survival improved between 2002 and 2010, according to newly published data.

WASHINGTON — Patients with primary biliary cirrhosis treated with obeticholic acid showed improvements in plasma alkaline phosphatase, according to findings presented here.

WASHINGTON — Assessing cirrhotic patients for urine neutrophil gelatinase-associated lipocalin at hospital admission may predict mortality associated with acute kidney injury, according to findings presented here.