Cirrhosis/Liver Failure News

In a new clinical study, researchers found that Olysio combined with Sovaldi with or without ribavirin had a higher efficacy rate and lower rate of adverse events among patients with Child-Pugh A cirrhosis vs. patients with Child-Pugh B/C cirrhosis.

Antiviral therapy without interferon improved liver function in patients with hepatitis C virus infection-related advanced cirrhosis, according to data from an observational cohort study.

Antibodies for the soluble liver antigen/liver pancreas antigen and diagnosis of cirrhosis before 18 years of age were found to be major risk factors for poor short- and long-term outcomes in patients with autoimmune hepatitis, including a reduced overall survival, according to study data published in Hepatology.

Intercept Pharmaceuticals Inc. announced the FDA has accepted the company's New Drug Application for review, as well as granted priority review for obeticholic acid for the treatment of primary biliary cirrhosis, according to a press release.

Liver transplant recipients treated with ursodeoxycholic acid had a lower risk for recurrent primary biliary cirrhosis, according to published findings in the Journal of Hepatology.

Researchers from the University of Padova in Italy found that an antibiotic combination regimen of Merrem and Cubicin was more effective in treating nosocomial spontaneous bacterial peritonitis compared with Glazidim, according to published findings.

In a retrospective study, researchers found that survival in patients with cirrhosis following admission to an intensive care unit increased over the last decade, and sequential organ failure assessment and chronic liver failure-sequential organ failure assessment scores were similar in predicting patient survival, according to published findings.

In a new study, researchers found that Olysio combined with Sovaldi with or without ribavirin yielded a sustained virologic response in patients with hepatitis C virus genotype 1 infection with liver cirrhosis, according to published findings in Hepatology.

New research data published in EBioMedicine showed that limonene, methanol and 2-pentanone were useful breath biomarkers for diagnosing cirrhosis.

Diabetes was found to be associated with an increased risk of first-time overt hepatic encephalopathy among patients with cirrhosis and ascites, according to data published in the Journal of Hepatology.