Cirrhosis/Liver Failure News

The Quick Sequential Organ Failure Assessment, or qSOFA, scoring system captured the difference in pathophysiology and hemodynamic status of patients with cirrhosis and infections as well as predicted ICU admission, according to a recent study.

Recently published data showed that Japan Hepatic Encephalopathy Prediction Model, or JHEPM, probability and prothrombin-time international ratio values can be used as predictive measures for the progression from acute liver injury to acute liver failure.

Results of a systematic review and meta-analysis showed a probable association between statin use and a lower risk for hepatic decompensation and mortality in patients with chronic liver disease. Further, statin use may reduce portal hypertension in these patients.

CHICAGO — Cognitive function improves in most patients who undergo liver transplantation for cirrhosis, according to a presentation at Digestive Disease Week. However, in those who do not improve, researchers have found an increase in Proteobacteria that could be associated with incomplete brain recovery for select patients.

CHICAGO — In a safety-net hospital system study, researchers found that nearly 30% of patients with chronic hepatitis B had cirrhosis at initial presentation, especially men, older patients and patients with non-alcoholic fatty liver disease, according to a presentation at Digestive Disease Week.

Although the death rate for blacks declined 25% from 1999 to 2015, there are still disparities between blacks and whites, according to a recent CDC Vital Signs report. In addition, blacks are living longer, but their life expectancy is still 4 years less than that of whites.

CHICAGO — A research team identified genetic markers that predict which patients with hepatitis C and cirrhosis will most likely improve with direct-acting antiviral agent and those who will fail to improve or possibly worsen, according to a presentation at Digestive Disease Week.

AMSTERDAM — At this year’s International Liver Congress, EASL presented new clinical practice guidelines for the diagnosis, management and treatment of hepatitis B, primary biliary cholangitis, primary sclerosing cholangitis, alcoholic liver disease and acute liver failure.

AMSTERDAM — EASL recently published their new clinical practice guideline on the assessment and management of acute liver failure, presented recently at the International Liver Congress.

AMSTERDAM — Severe periodontitis predicts higher cause mortality among patients with cirrhosis, according to data presented at the International Liver Congress.