Cirrhosis/Liver Failure News

Results from the STELLAR-4 phase 3 study showed that selonsertib did not meet the pre-specified 48-week endpoint of histologic improvement by 1 or more stage in fibrosis without worsening of nonalcoholic steatohepatitis, according to a press release.

Results of a prospective study showed that treatment with direct-acting antivirals for hepatitis C correlated with significantly reduced risks for hepatocellular carcinoma and mortality, according to a study published in The Lancet.

More than half of patients who presented in hospital with acetaminophen-induced acute liver injury or acute liver failure had undetectable levels of acetaminophen, according to a study recently published in Clinical Gastroenterology and Liver Disease.

EASL announced the formation and official launch of MICROB-PREDICT, a project designed to research the human microbiome for clinical research and therapeutic development in the field of decompensated cirrhosis and acute-on-chronic liver failure, according to a press release.

Among the three largest Hispanic population subgroups, researchers found high levels of heterogeneity in chronic liver disease-related mortality patterns, according to a recently published study.

Patients undergoing direct-acting antiviral therapy for hepatitis C who had non-characterized liver nodules had a higher risk for hepatocellular carcinoma within a short follow-up time than other patients, according to a recently published study.

Fecal microbiota transplant after antibiotic treatment may be safe and potentially prevent long-term recurrence of hepatic encephalopathy in patients with cirrhosis, according to extended data from a previously published study.

Researchers found that while acute-on-chronic liver failure prevalence decreased over a 10-year period, overall survival of patients with grade 3 acute-on-chronic liver failure did not improve, according to data published in Journal of Hepatology.

Alterations in iron parameters correlated with 3-week outcomes in patients with acute liver failure and may serve as a useful component in prognostic scores, according to a study published in Hepatology.

Researchers observed significant fibrosis in more than one-third of patients with hepatitis B and HIV coinfection undergoing long-term combination antiretroviral therapy with viral suppression, according to a study published in American Journal of Gastroenterology.