Chronic Hepatitis News

Current WHO guidelines for chronic hepatitis B failed to detect half of the patients in need of treatment in Ethiopia and more than half of those who met eligibility criteria had developed decompensated cirrhosis.

Many chronic liver complications such as autoimmune hepatitis and nonalcoholic fatty liver disease do not have approved therapies for direct treatment, but the current hepatology pipeline includes several candidates that have recently demonstrated safety in early trials and some that met top-line phase 3 results.

According to a study published in Hepatology, small dense LDL cholesterol independently predicted cardiovascular disease events among liver transplant recipients, according to a study published in Hepatology.

The U.S. Department of Veterans Affairs announced that it is on track to eliminate hepatitis C in all veterans willing and able to receive treatment within a timeframe of two months, according to a press release from the office.

Twelve weeks of combination Sovaldi and NS5A inhibitors without ribavirin was a reliable therapy with high rates of sustained virologic response for recurrent hepatitis C after liver transplantation, according to a study published in Hepatology.

Kidney transplant recipients with hepatitis B and hepatitis C in whom viral replication was controlled had similar overall and graft survival rates as patients without viral hepatitis, according to data published in Journal of Hepatology.

The current options for targeting hepatitis B include vaccination as prevention and immunomodulatory therapies for treatment. While the concept of a functional cure is beginning to gain some grounds, it is years away. For now, researchers continue to focus on discerning risk factors and disease progression to help patients.

Long-term surveillance among men who have sex with men with HIV after clearance of hepatitis C may be warranted as reinfection rates remain high and continue to occur more than 11 years after clearance regardless of treatment, according to a study presented at CROI.

The rates of hepatitis C incidence among men who have sex with men with HIV has significantly decreased in London since the epidemic peak in 2015, coinciding with wider access to direct-acting antiviral therapy, according to data presented at CROI.

Between 2005 and 2017, countries in the Western Pacific Region achieved marked progress toward hepatitis B control and elimination of mother-to-child transmission through increased vaccination among newborns, according to a report from the CDC.