Sarcoma News

The addition of olaratumab to doxorubicin significantly prolonged OS in patients with advanced soft tissue sarcoma, according to phase 2 study results.

Cardiac biomarkers troponin I and B-type natriuretic peptide may provide an effective strategy for the early detection of cardiotoxicity during anthracycline chemotherapy, researchers reported in the Journal of Cardiac Failure.

CHICAGO — Extending anticoagulation beyond 3 months reduced risk for recurrent clots in patients with cancer, according to results presented at the ASCO Annual Meeting.

CHICAGO — Despite global variance in cancer drug prices, generic and patented drugs are less affordable in low-income countries, according to a pilot study presented at the ASCO Annual Meeting.

CHICAGO — Liquid biopsy identified genomic alterations in patients with advanced solid tumors at a similar rate to traditional tumor biopsy, according to data presented at the ASCO Annual Meeting.

Patients with cancer who undergo chemotherapy may be at elevated risk for a new primary cancer several years later.

The TP53 gene mutation may predict improved response to VEGF receptor inhibition among patients with advanced sarcomas, according to a retrospective chart review.

Previous investigations conducted by the founders of the linear no-threshold model with respect to genetic effects and carcinogenesis represent “one of the greatest misapprehensions and oversight failures within the scientific research community,” according to authors of a study review published in American Journal of Clinical Oncology.

An assessment tool comprised of clinically relevant questions and specific treatment information accurately predicted risk for chemotherapy toxicity in a majority of older patients with cancer, according to the results of a validation study.

Male survivors of childhood cancer diagnosed before age 25 years appeared less likely to have children and more likely to require assisted reproduction than men who did not have cancer, according to results of a national cohort study.