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Sarcoma News
Six important FDA updates
The FDA has announced several decisions related to hematology and oncology treatments in the past 2 weeks.
FDA approves Lartruvo for soft tissue sarcoma
The FDA granted accelerated approval to olaratumab injection for use in combination with doxorubicin to treat adults with soft tissue sarcoma.
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Pomalidomide exhibits efficacy in Kaposi sarcoma, regardless of HIV status
Treatment with pomalidomide induced rapid responses in patients with Kaposi sarcoma, regardless of their HIV status, according to study results published in Journal of Clinical Oncology.
Standard neoadjuvant chemotherapy improves OS, RFS in soft tissue sarcoma
COPENHAGEN, Denmark — Neoadjuvant chemotherapy with three full-dose courses of an anthracycline plus ifosfamide improved OS and RFS compared with histology-tailored regimens in patients with localized soft tissue sarcoma at high risk for relapse, according to interim results of a randomized trial presented at the European Society for Medical Oncology Congress.
Survivors of fusion-negative sarcoma at increased risk for second malignancies
Survivors of sarcoma demonstrated an increased risk for second malignant neoplasms, according to study results published in Cancer. Survivors of fusion-negative tumors faced a greater risk than those with fusion-positive tumors.
AACR report: Sustained federal commitment required to accelerate cancer research progress
Extraordinary therapeutic advances, a renewed bipartisan commitment to medical research and the launch of the national cancer moonshot initiative have reinforced the importance of scientific investigation in the fight against cancer.
Biden announces steps to improve clinical trials under cancer moonshot
Vice President Joe Biden outlined a plan to improve the efficiency and transparency of the U.S. clinical research system as part of the national cancer moonshot initiative.
NCHS data brief: 20% decline in children’s cancer death rate ‘builds upon 3 decades of progress’
The U.S. death rate of children and adolescents with cancer continues to decline with a 20% drop over a 15-year span, according to a data brief report from the CDC’s National Center for Health Statistics.
Genomic variants, genetic testing may identify ‘sarcoma families’
More than one-half of patients with sarcoma harbored putatively pathogenic monogenic and polygenic mutations to known cancer genes, according to study results published in The Lancet Oncology.
Blue ribbon panel presents research road map for cancer moonshot initiative
The national cancer moonshot initiative’s blue ribbon panel delivered 10 recommendations to form a 5-year research blueprint to accelerate progress against cancer at the NCI’s National Cancer Advisory Board meeting.
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