Sarcoma News

WAILEA, Hawaii — Neoadjuvant larotrectinib enabled children with NTRK-fusion advanced sarcomas to proceed to surgery without increasing the risk for postsurgical complications or wound healing issues, according to phase 1/phase 2 study results presented at the Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — Surgical margin status is the only key factor that should guide decisions about adjuvant radiation therapy for patients with surgically resected osteosarcomas of the head and neck, according to study results presented at Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — Not all cases of synovial sarcoma of the extremities result in severe outcomes, according to study results presented at Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — The safety and efficacy of trabectedin for advanced leiomyosarcoma or liposarcoma appeared comparable among older and younger patients, according to a multicenter, open-label study presented at the Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — Characteristics including tumor size, invasion, necrosis and infiltrative growth helped identify patients with soft tissue sarcoma at high risk for metastasis who benefited from adjuvant chemotherapy plus accelerated radiotherapy, according to prospective, nonrandomized study results presented at the Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — The combination of axitinib and pembrolizumab demonstrated early evidence of activity among patients with advanced alvelor soft part sarcoma and other soft tissue sarcomas, according to phase 2 study results presented at the Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — The combination of durvalumab and tremelimumab appeared safe and demonstrated modest activity for heavily pretreated patients with a variety of sarcoma subtypes, according to single-center phase 2 study results presented at the Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — Preoperative radiotherapy did not reduce risk for mortality, local tumor recurrence or metastasis among patients who underwent surgical treatment for sacral chordoma, according to study results presented at Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — Many sarcoma cases had inaccurate ICD-9/ICD-10 coding, which could affect the accuracy of the National Cancer Data Base, National Inpatient Sample and other national databases, according to study results presented at the Connective Tissue Oncology Society Annual Meeting.

WAILEA, Hawaii — The risk for needle tract recurrence after core needle biopsy for retroperitoneal sarcoma appeared low, according to study results presented at Connective Tissue Oncology Society Annual Meeting.