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Sarcoma News
Ripretinib fails to improve PFS in advanced gastrointestinal stromal tumor
Ripretinib did not extend PFS compared with sunitinib for patients with advanced gastrointestinal stromal tumor who previously received imatinib, according to randomized phase 3 study results presented during the ASCO Plenary Series.
FDA grants rare pediatric disease designation to IMX-110 for rhabdomyosarcoma
The FDA granted rare pediatric disease designation to IMX-110 for treatment of children with rhabdomyosarcoma.
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FDA approves Fyarro for perivascular epithelioid cell tumor
The FDA approved sirolimus protein-bound particles for injectable suspension (albumin-bound) for treatment of adults with locally advanced unresectable or metastatic malignant perivascular epithelioid cell tumor.
TCR T-cell therapy induces response in solid cancers
Half of patients with relapsed or refractory solid tumors achieved objective response to an infusion of IMA203, according to study results presented at Society for the Immunotherapy of Cancer Annual Meeting.
Ripretinib trial misses primary endpoint for patients with gastrointestinal stromal tumor
Ripretinib failed to prolong PFS compared with sunitinib among patients with gastrointestinal stromal tumor who received prior treatment with imatinib, according to results of the phase 3 INTRIGUE study released by the agent’s manufacturer.
Whole-genome methylation shows promise as multicancer early-detection test
Evaluation of multiple classifiers, both alone and in combination, supports the decision to focus on cell-free DNA methylation patterns to detect cancer and predict the cancer signal origin, according to a presentation at ESMO Congress 2021.
Should collection of sexual orientation and gender identity data be mandated?
To advance health equity, it is time to normalize the collection of sexual orientation and gender identity (SOGI) data in clinical practice and in health services research.
‘Knowledge gap’ hinders efforts to improve care of LGBTQ+ patients
Standard cancer care may fail to adequately address the needs of LGBTQ+ individuals, who face substantial disparities in access to screening, treatment and outcomes.
T-cell receptor therapy ‘definitely effective’ for metastatic solid tumors
More than a third of patients with solid tumors showed evidence of antitumor response after treatment with ADP-A2M4CD8, according to data presented at the virtual ESMO Congress.
CRISPR gene editing may put universal T-cell therapy within reach
Few scientific advances have generated the optimism and enthusiasm that surround CRISPR.
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Headline News
‘We have a home’: Physician aims to create network of women allergists
November 14, 20245 min read -
Headline News
Diversified portfolios allow for ‘smoother ride’
November 14, 20243 min read -
Headline News
Predelivery concussion linked to increased risk for severe maternal mental illness
November 12, 20242 min read