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Melanoma/Skin Cancer News
Cemiplimab improves pain, quality of life in patients with advanced cSCC
Patients treated with cemiplimab for advanced cutaneous squamous cell carcinoma had improvements to quality of life, pain and other symptoms, according to a presentation at South Beach Symposium Medical Dermatology Summit.
Klisyri superior to placebo for treatment of actinic keratoses in randomized studies
Klisyri, an FDA-approved Src kinase signaling inhibitor, was superior to placebo for the treatment of actinic keratoses, according to findings from two double-blind randomized trials published in The New England Journal of Medicine.
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FDA approves Libtayo for advanced basal cell carcinoma
The FDA granted regular approval to cemiplimab-rwlc for patients with locally advanced basal cell carcinoma who were previously treated with or ineligible for treatment with a hedgehog pathway inhibitor.
Hedgehog inhibitor treatment patterns vary by grace period
Patients with basal cell carcinoma who discontinued hedgehog inhibitors had differing odds for reinitiation that varied by grace period, according to a presentation at Maui Derm for Dermatologists.
FDA grants fast track designation to TH1902 for sortilin-expressing cancers
The FDA granted fast track designation to TH1902 for treatment of certain patients with sortilin-expressing cancers, according to the agent’s manufacturer.
Cemiplimab has ‘increasing, clinically meaningful’ duration of response in advanced cSCC
Patients with advanced cutaneous squamous cell carcinoma had an “increasing, clinically meaningful” duration of response with cemiplimab, according to results from a phase 2 study presented at Maui Derm for Dermatologists.
FDA grants fast track designation to toripalimab for mucosal melanoma
The FDA granted fast track designation to toripalimab for the first-line treatment of patients with mucosal melanoma, according to a manufacturer-issued press release.
Anal carcinoma risk elevated in individuals with HIV and anogenital warts
Anal carcinoma risk was significantly higher among individuals with HIV and a history of anal or genital warts than among those with no history of these warts, according to a study.
FDA grants fast track designation to AST-008 for skin cancer indications
The FDA granted fast track designation to cavrotolimod for two skin cancer indications, according to the agent’s manufacturer.
New approach generates more effective adoptive T-cell therapies faster, with fewer cells
Adoptive cell therapies have proved highly effective for patients with certain advanced cancers, particularly melanoma and hematologic malignancies.