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Melanoma/Skin Cancer News
Parker Institute for Cancer Immunotherapy awards research grants
The Parker Institute for Cancer Immunotherapy awarded nearly $3 million worth of grants to six early career researchers.
Oncologist joins Parker Institute for Cancer Immunotherapy as senior VP
Ute Dugan, MD, PhD, has been appointed senior vice president for clinical research at Parker Institute for Cancer Immunotherapy.
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Cemiplimab has ‘clinical benefit’ in locally advanced BCC after hedgehog inhibitor use
Patients previously treated with hedgehog inhibitors for locally advanced basal cell carcinoma saw “clinical benefit” when treated with cemiplimab, according to a presentation at South Beach Symposium Medical Dermatology Summit.
EGFR inhibitors in cancer treatment may be associated with adverse cutaneous events
A number of epidermal growth factor receptor inhibitors used in the oncology setting continue to demonstrate impacts on keratinocyte growth and cause adverse skin reactions, according to a study.
Women may have better survival than men in Merkle cell carcinoma
Mortality associated with Merkle cell carcinoma may be lower among women compared with men, according to a retrospective study.
Pathological response to neoadjuvant therapy correlates to RFS, OS in stage III melanoma
Pathological response should be an early surrogate endpoint for clinical trials of neoadjuvant therapy for melanoma, according to results of a pooled analysis published in Nature Medicine.
Sonidegib not affected by cardiovascular medications in locally advanced BCC
Sonidegib efficacy in patients with locally advanced basal cell carcinoma was not affected by concomitant cardiovascular medications, according to a presentation at Maui Derm for Dermatologists.
Checkpoint inhibitor response, adverse event rate similar regardless of autoimmune disease
Patients’ response to anti-CTLA-4 or anti-PD-1 checkpoint therapy for advanced melanoma, and their incidence of immune-related adverse events of grade 3 or higher, were similar regardless of preexisting autoimmune disease, according to data.
Dabrafenib plus trametinib improves relapse-free survival time in melanoma
Patients with a stage III melanoma mutation treated with dabrafenib plus trametinib had longer restricted mean survival times compared with placebo, according to an analysis of a phase 3 trial presented at Maui Derm for Dermatologists.
Circulating tumor DNA could help guide treatment of BRAF V600-mutant metastatic melanoma
Circulating tumor DNA measurements before and during treatment could help guide selection of therapy for patients with BRAF V600-mutant unresectable or metastatic melanoma, according to study results published in The Lancet Oncology.