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Melanoma/Skin Cancer News
Thiazides associated with increased risk for skin cancer in older adults
Adults aged over 65 years who took thiazides for hypertension had an increased risk for keratinocyte carcinoma and melanoma, according to results of a population-based cohort study.
Tebentafusp improves OS in advanced uveal melanoma
Tebentafusp significantly prolonged OS compared with immune checkpoint inhibitors and other standard therapies among previously untreated patients with metastatic uveal melanoma, results of a randomized phase 3 study showed.
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Adolescents and young adults with cancer require dedicated services, research
Going through cancer during transitional adolescent and young adult years can present additional social, financial and mental health challenges that add to the stressors of diagnosis and treatment.
Survival after Mohs surgery for invasive melanoma associated with treatment facility
Early-stage invasive melanoma excised with Mohs micrographic surgery at academic and top decile-volume facilities was associated with improved long-term survival, according to a study published in JAMA Dermatology.
Older patients with actinic keratosis at risk for cSCC
Diagnosis with actinic keratosis at age younger than 49 years or older than 80 years was associated with elevated cutaneous squamous cell carcinoma risk, according to a study.
Larger surgical margins improved survival in localized Merkel cell carcinoma
Among patients with localized Merkel cell carcinoma, surgical margins larger than 1 cm improved survival regardless of factors such as tumor subsite and receipt of adjuvant chemotherapy, according to a study.
Structured surveillance program may have utility in high-risk melanoma
A large-scale surveillance program may allow clinicians to detect melanomas earlier in high-risk patients, according to a study.
Chronic adverse events more common than thought after adjuvant immunotherapy for melanoma
Chronic immune-related adverse events appeared more common than previously thought among patients with stage III to stage IV melanoma who received adjuvant anti-PD-1 therapy, according to study results published in JAMA Oncology.
Relatlimab-nivolumab combination extends PFS in metastatic melanoma
A trial designed to evaluate the addition of relatlimab to nivolumab for untreated metastatic or unresectable melanoma met its primary endpoint of improved PFS, according to topline data released by the agent’s manufacturer.
Tumor mutational burden does not predict response to immunotherapy in all cancer types
Tumor mutational burden predicted immunotherapy response for some, but not all, cancer types, according to study results published in Annals of Oncology.