Melanoma/Skin Cancer News

The increase in melanoma incidence has been caused by multiple factors, with overdiagnosis possibly playing a role, according to a review in the Journal of the American Academy of Dermatology.

For patients undergoing skin biopsies of melanocytic lesions, selective second opinions may lead to better diagnostic accuracy and less cost compared with no second opinions or universal second opinions, according to a study.

Use of alrizomadlin with pembrolizumab appeared to restore the antitumor effects of the anti-PD-1 antibody among patients with melanoma resistant to or intolerant of immunotherapy, according to phase 2 study results.

Pembrolizumab induced an overall response rate among patients with high-risk melanoma who relapsed on placebo comparable to that expected among treatment-naive patients, according to results from the EORTC 1325/KEYNOTE-054 trial.

Pembrolizumab extended RFS compared with high-dose interferon or ipilimumab as adjuvant therapy for patients with high-risk melanoma, according to randomized phase 3 study results presented during the virtual ASCO Annual Meeting.

IACS-6274, a selective glutaminase-1 inhibitor, appeared safe and demonstrated antitumor activity among patients with biomarker-selected advanced solid tumors, according to phase 1 study results presented at the virtual ASCO Annual Meeting.

Andrew E. Aplin, PhD, has been appointed deputy director for scientific strategy at Sidney Kimmel Cancer Center — Jefferson Health.

The addition of relatlimab to nivolumab conferred a significant PFS benefit among treatment-naive patients with advanced melanoma, according to results of the phase 2/phase 3 RELATIVITY-047 study presented at the virtual ASCO Annual Meeting.

Treatment of melanoma in situ with Mohs micrographic surgery may have better outcomes than treatment with wide local excision, according to a study presented at AAD VMX 2021.

Female patients with melanoma on immune checkpoint inhibitor therapy exhibited higher rates of dermatologic adverse events compared with male patients, according to a study presented at AAD VMX 2021.