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Lymphoma News
CAR-T provides value despite high price tag, oncologists say
Sixty percent of hematologist-oncologists believe chimeric antigen receptor T-cell therapies provide clinical value at their current price, according to survey results presented at ASH Annual Meeting and Exposition.
Circulating tumor DNA profiling may allow for surgery-free detection of CNS lymphoma
Circulating tumor DNA can be readily detected in patients with central nervous system lymphoma and may be a strong clinical biomarker for risk stratification, outcomes prediction and surgery-free lymphoma classification, results showed.
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Age, sex, other factors impact mortality risk among patients with blood cancer, COVID-19
Older age, male sex, pre-COVID-19 prognosis of less than 6 months and deferral of ICU care appeared associated with greater risk for mortality among patients with blood cancer and COVID-19, study results showed.
Mosunetuzumab shows deep, durable responses in advanced follicular lymphoma
Mosunetuzumab more than quadrupled the complete response rate among patients with relapsed or refractory follicular lymphoma, according to results of a pivotal phase 2 study.
Certain patients with hematologic diseases have poor, no response to COVID-19 vaccination
Nearly one in six patients with hematologic disorders had a negative COVID-19 vaccination-related antibody response, according to results of a prospective, observational single-center study presented at ASH Annual Meeting and Exposition.
Liso-cel significantly improves outcomes in second-line DLBCL
Second-line lisocabtagene maraleucel more than quadrupled EFS compared with standard therapy for patients with relapsed or refractory large B-cell lymphoma, according to study results presented at ASH Annual Meeting and Exposition.
EFS improvement with axi-cel CAR-T a ‘breakthrough’ in second-line treatment of DLBCL
Second-line therapy with axicabtagene ciloleucel conferred a fourfold increase in EFS compared with standard-of-care treatment for diffuse large B-cell lymphoma, according to results of a randomized phase 3 study.
FDA official to receive ASH Outstanding Service Award
The American Society of Hematology will present this year’s ASH Outstanding Service Award to Peter Marks, MD, PhD.
FDA approves Rituxan plus chemotherapy for pediatric lymphoma, leukemia
The FDA approved rituximab in combination with chemotherapy for several pediatric cancer indications.
Award recipient’s advice to early-career oncologists: ‘Do not be bashful,’ ask questions
The William L. McGuire Lecture Award will be presented to Olufunmilayo Olopade, MD, FAACR, at San Antonio Breast Cancer Symposium this month.