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Lymphoma News
IgG4-related disease linked to increased risk for lymphoma, pancreatic cancer
Patients with IgG4-related disease are at a higher risk for cancer — particularly pancreatic and lymphoma — compared with the general population, according to a meta-analysis published in Arthritis Research & Therapy.
Gilead withdraws Zydelig indication for lymphoma, leukemia subtypes
Gilead Sciences has decided to voluntarily withdraw its accelerated approval of idelalisib for two blood cancer indications.
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FDA grants fast track, RMAT designations to bispecific CAR-T for non-Hodgkin lymphoma
The FDA granted fast track and regenerative medicine advanced therapy designations to C-CAR039, a chimeric antigen receptor T-cell therapy in development for treatment of relapsed or refractory diffuse large B cell lymphoma.
Allogeneic CAR-T induces high response rates in non-Hodgkin lymphoma, B-cell ALL
An enhanced lymphodepletion regimen followed by chimeric antigen receptor T-cell therapy induced response among patients with relapsed or refractory B-cell malignancies, according to results presented at ASH Annual Meeting and Exposition.
FDA lifts clinical hold on Allogene’s CAR T-cell therapy trials
The FDA lifted its clinical hold on a series of trials that use Allogene Therapeutics’ AlloCAR T chimeric antigen receptor T-cell therapies, according to a press release from the manufacturer.
COVID-19 mortality risk higher among older patients with B-cell malignancies
Older patients with B-cell malignancies diagnosed with COVID-19 had a substantially higher risk for death than their counterparts aged 60 years or younger, according to study results published in JCO Oncology Practice.
Safety an ‘important differentiating factor‘ for novel CAR-T in B-cell malignancies
A chimeric antigen receptor T-cell therapy induced high response rates across a range of B-cell malignancies, according to phase 1 study results presented at ASH Annual Meeting and Exposition.
COVID-19 vaccine booster dose benefits patients with cancer
Patients with cancer who had no measurable immune response following full COVID-19 vaccination had “excellent potentiation” after receiving a third, booster dose, according to results of a study in Cancer Cell.
Patients with cancer at high risk for death due to breakthrough COVID-19 infections
Fully vaccinated patients with cancer who developed breakthrough COVID-19 infections appeared at high risk for hospitalization and death, according to study results published in Annals of Oncology.
Residents of low-income, rural areas at higher risk for suicide after cancer diagnosis
Patients with cancer who resided in low-income and rural areas appeared at higher risk for suicide than those in high-income and urban areas, according to a retrospective, population-based study in JAMA Network Open.