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Lymphoma News
CAR-T poised to create ‘paradigm shift’ in non-Hodgkin lymphoma
Since the approval of the first chimeric antigen receptor T-cell therapy, the research community has grappled with a crucial question.
Scoring system predicts infection risk, treatment outcomes after CAR-T
Researchers from Europe and the U.S. developed a hematologic toxicity score that can predict which patients are more likely to develop severe infections after chimeric antigen receptor T-cell therapy.
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FDA clears INDs for cell therapies to treat multiple cancer types
The FDA cleared investigational new drug applications for three cell therapies in development for oncology indications.
Septic shock linked to high mortality rates among patients with hematologic malignancies
Septic shock remained significantly associated with increased 28-day mortality among patients with hematologic malignancies, according to study results published in Journal of the National Comprehensive Cancer Network.
Multiple myeloma specialist named inaugural director of blood cancer center
Faith E. Davies, MD, has been appointed the inaugural director of Center for Blood Cancers at NYU Langone Health’s Perlmutter Cancer Center.
Addition of brentuximab vedotin to chemotherapy extends OS in advanced Hodgkin lymphoma
The addition of brentuximab vedotin to front-line chemotherapy reduced risk for death by 41% among patients with newly diagnosed advanced classical Hodgkin lymphoma, according to topline data released by the agent’s manufacturer.
FDA investigates potential increased death risk with lymphoma therapy Ukoniq
The FDA is investigating a possible increased mortality risk with umbralisib, approved in the United States for treatment of two types of lymphoma.
Biden relaunches Moonshot with aim to cut cancer deaths by at least 50% in 25 years
President Joe Biden has unfinished business with cancer.
FDA updates Yescarta label to include use of prophylactic steroids for toxicity management
The FDA updated the prescribing information for axicabtagene ciloleucel to allow the use of prophylactic corticosteroids to manage the severity of certain treatment-related adverse events.
Tofacitinib linked to higher cardiovascular, cancer risks than TNF inhibitors in RA
Patients with rheumatoid arthritis who received tofacitinib demonstrated a greater risk for major adverse cardiovascular events and cancer than those treated with TNF inhibitors, according to data in The New England Journal of Medicine.