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Leukemia News
COVID-19 more severe in patients with active acute leukemia, myelodysplastic syndrome
Patients with acute leukemia or myelodysplastic syndrome in an active state experienced significantly greater COVID-19 severity but not higher mortality due to the virus, according to research presented at ASH Annual Meeting and Exposition.
Addition of gilteritinib to azacitidine may benefit certain patients with FLT-mutated AML
Gilteritinib plus azacitidine conferred significantly higher complete remission rates, but similar OS, vs. azacitidine among patients with newly diagnosed, FLT3-mutated acute myeloid leukemia ineligible for intensive induction chemotherapy.
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Venetoclax-based time-limited combination therapies show efficacy in CLL
Time-limited venetoclax-based combination therapies conferred superior rates of undetectable minimal residual disease compared with chemoimmunotherapy among fit patients with chronic lymphocytic leukemia, study results showed.
Ibrutinib plus chemoimmunotherapy confers durable responses in younger patients with CLL
Most patients with chronic lymphocytic leukemia who received ibrutinib plus fludarabine, cyclophosphamide and rituximab continued to maintain deep responses after longer-term follow-up, results of a single arm, phase 2 trial showed.
AML in younger Black AYAs molecularly distinct, associated with shorter survival
Younger Black patients with acute myeloid leukemia had worse outcomes than their white counterparts, including a higher early death rate, numerically lower complete remission rate and shorter OS, according to study results.
Addition of venetoclax to azacitidine improves outcomes for subset of patients with AML
Treatment with venetoclax plus azacitidine conferred better outcomes than azacitidine alone among select patients with acute myeloid leukemia, according to study results presented at ASH Annual Meeting and Exposition.
Age, sex, other factors impact mortality risk among patients with blood cancer, COVID-19
Older age, male sex, pre-COVID-19 prognosis of less than 6 months and deferral of ICU care appeared associated with greater risk for mortality among patients with blood cancer and COVID-19, study results showed.
Most patients with AML, myelodysplastic syndrome seropositive after two COVID vaccine doses
A vast majority of patients with acute myeloid leukemia and myelodysplastic syndrome converted to seropositivity after two COVID-19 vaccine doses, according to a study presented at ASH Annual Meeting and Exposition.
Ivosidenib regimen extends OS, EFS for acute myeloid leukemia subset
The addition of ivosidenib to azacitidine improved outcomes for certain patients with acute myeloid leukemia, according to study results presented at ASH Annual Meeting and Exposition.
Racial disparities persist among young patients with acute lymphoblastic leukemia
Considerable survival gaps exist among young white, Black and Hispanic individuals with acute lymphoblastic leukemia, according to study results presented at ASH Annual Meeting and Exposition.
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Headline News
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Culture shift needed to reframe cybersecurity as a patient safety issue
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Headline News
Q&A: Cuts to 2025 physician fee schedule yield ‘catastrophic’ impacts to patient access
November 11, 20246 min read -
Headline News
Daily oral semaglutide confers weight loss vs. placebo; similar vs. weekly injectables
November 11, 20243 min read -
Headline News
Culture shift needed to reframe cybersecurity as a patient safety issue
November 11, 202410 min read