Leukemia News

The 2-year OS rate nearly doubled during the past 2 decades among patients with Philadelphia chromosome-positive acute lymphoblastic leukemia who relapsed after allogeneic hematopoietic stem cell transplantation, according to study results.

Less than one-third of hospitals had access to the life-saving agent all-trans retinoic acid for patients with acute promyelocytic leukemia, according to study results published in Journal of the National Comprehensive Cancer Network.

The FDA granted breakthrough device designation to BNT200.

Depletion of naive T cells from peripheral blood stem cell grafts resulted in very low incidence of severe acute and any graft-versus-host disease in three phase 2 clinical trials, according to a study in Journal of Clinical Oncology.

Individuals with acute myeloid leukemia in remission after hematopoietic stem cell transplantation reported ongoing symptoms and impacts in the post-transplant period, according to research presented at ASH Annual Meeting and Exposition.

Older patients with B-cell malignancies diagnosed with COVID-19 had a substantially higher risk for death than their counterparts aged 60 years or younger, according to study results published in JCO Oncology Practice.

Younger Hispanic/Latinx patients face many barriers that may limit timely access to chimeric antigen receptor T-cell therapy trials for relapsed or refractory B-cell acute lymphoblastic leukemia, according to retrospective study results.

A chimeric antigen receptor T-cell therapy induced high response rates across a range of B-cell malignancies, according to phase 1 study results presented at ASH Annual Meeting and Exposition.

Patients with cancer who had no measurable immune response following full COVID-19 vaccination had “excellent potentiation” after receiving a third, booster dose, according to results of a study in Cancer Cell.

Fully vaccinated patients with cancer who developed breakthrough COVID-19 infections appeared at high risk for hospitalization and death, according to study results published in Annals of Oncology.