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Hematology News
Will new therapies for sickle cell disease lead to a change or reduction in use of hydroxyurea for the management of pain?
Click here to read the Cover Story, “Sickle cell disease poised for ‘golden age of treatment’ amid progress toward cure.”
Sickle cell disease poised for ‘golden age of treatment’ amid progress toward cure
As researchers work to expand curable approaches for sickle cell disease, new options for managing its acute and chronic complications appear within reach.
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Rivaroxaban reduces VTE among ambulatory patients with pancreatic cancer
CHICAGO — Rivaroxaban thromboprophylaxis greatly reduced venous thromboembolism among ambulatory patients with pancreatic cancer, according to results of a prespecified subgroup analysis of the CASSINI study presented at ASCO Annual Meeting.
‘Platelet decoys’ may lower blood clot risk, prevent cancer metastasis
A novel antiplatelet therapy showed potential in reducing blood clot risk and preventing cancer metastasis, according to preclinical research findings published in Science Translational Medicine.
Strategies to identify sickle cell disease among refugees could reduce complications, costs
Refugees arriving in Europe from countries with high rates of sickle cell disease should be immediately screened for the disease to help prevent acute crises and potentially fatal complications, according to results of a retrospective study published in Blood.
FDA approves Fragmin, first anticoagulant for children
The FDA today approved dalteparin sodium injection to reduce the recurrence of symptomatic venous thromboembolism among children aged at least 1 month.
Higher radiation dose safely reduces graft failure after haploidentical bone marrow transplantation
Increasing the dose of total body irradiation to 400 cGy from 200 cGy greatly reduced graft failure among patients with sickle cell disease or beta-thalassemia who received a haploidentical bone marrow transplant with post-transplantation cyclophosphamide, according to results of a phase 2 prospective study published in The Lancet Haematology.
‘Tremendous racial and ethnic disparity’ observed in access to matched donor stem cells
Patients with cancer who need a bone marrow transplant are less likely to find a suitable match if they are of southern-European or non-European descent, according to results of a prospective study published in Blood Advances.
Will heparin eventually be phased out with expanded use of DOACs for VTE?
Click here to read the Cover Story, “Venous thromboembolism guidelines aim to clarify proper care in areas with ‘a lot of uncertainty.’”
Venous thromboembolism guidelines aim to clarify proper care in areas with ‘a lot of uncertainty’
Venous thromboembolism — which includes deep vein thrombosis and pulmonary embolism — causes up to 100,000 deaths annually in the United States and affects patients in numerous health care settings, regardless of age.