Hematology News

The use of gene-edited stem cells has shown early positive results among patients with sickle cell disease and transfusion-dependent beta-thalassemia, according to data presented at the virtual ASH Annual Meeting and Exposition.

An off-the-shelf, virus-specific T-cell therapy demonstrated proof of concept to enter a clinical trial for the treatment of severe COVID-19 infection, according to study results presented at the virtual ASH Annual Meeting and Exposition.

Over 40% of patients with severe COVID-19 improved within a week of convalescent plasma infusion, with more than 50% alive and discharged by 28 days, according to a study presented at the virtual ASH Annual Meeting and Exposition.

Despite promising data that have emerged on COVID-19 vaccine candidates, a return to normal “carefree” life is likely years out, according to Anthony S. Fauci, MD, director of the National Institute of Allergy and Infectious Diseases.

Researchers have found certain rare and pathogenic thrombotic microangiopathy-associated variants among patients with severe COVID-19, according to study results presented at the virtual ASH Annual Meeting and Exposition.

The addition of tranexamic acid prophylaxis to platelet transfusion did not reduce bleeding among patients with blood cancers and severe thrombocytopenia, according to study results presented at the virtual ASH Annual Meeting and Exposition.

Patients with sickle cell disease may be at higher risk for certain COVID-19 complications and death, according to results of two studies presented at ASH Annual Meeting and Exposition.

The FDA granted fast track designation to rilzabrutinib for treatment of immune thrombocytopenia, according to the agent’s manufacturer.

The FDA granted priority review to pegcetacoplan for treatment of paroxysmal nocturnal hemoglobinuria, according to the agent’s manufacturer.

Adults with Erdheim-Chester disease, a rare blood cancer, are more likely than those without the disease to have central or primary hypothyroidism and should be screened with a full thyroid panel, according to study findings.