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Hematology News
Agent exhibits ‘significant evidence of efficacy’ for infants with severe hemophilia A
NEW ORLEANS — Emicizumab-kxwh prophylaxis appeared effective and safe for infants with severe hemophilia A without factor VIII inhibitors, according to study results presented at ASH Annual Meeting and Exposition.
ASH presents Outstanding Service Award to former NHLBI director
Keith Hoots, MD, received ASH’s Outstanding Service Award.
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Tool may help identify which patients with clonal hematopoiesis will develop cancer
NEW ORLEANS — A new clinical tool can help identify which patients with clonal hematopoiesis are at highest risk for progression to cancer, according to study results presented at ASH Annual Meeting and Exposition.
ASH recognizes Choosing Wisely, Guideline Implementation champions
ASH recognized three Choosing Wisely champions and three guideline implementation champions at this year’s ASH Annual Meeting and Exposition.
ASH recap: New regimens for blood cancers; gene therapy equitable for sickle cell disease
This year’s ASH Annual Meeting and Exposition spotlighted practice-changing research in malignant and benign hematology.
Gene therapy restores immunity in Artemis-deficient severe combined immunodeficiency
Infants with Artemis-deficient severe combined immunodeficiency improved after corrected genes in their stem cells enabled them to grow their own T cells and B cells, according to a study published in The New England Journal of Medicine.
Use of blood thinners may be unnecessary in women with recurrent pregnancy loss
NEW ORLEANS — The use of low-molecular-weight heparin among pregnant women with a history of recurrent miscarriage and inherited thrombophilia had no effect on the live birth rate, results from the phase 3 ALIFE2 trial showed.
FDA lifts partial clinical hold on studies of gene therapy for sickle cell disease
The FDA lifted its partial clinical hold on bluebird bio’s sickle cell disease studies evaluating lovotibeglogene autotemcel among patients aged younger than 18 years, according to the agent’s manufacturer.
Iptacopan may become preferred treatment for hemolytic paroxysmal nocturnal hemoglobinuria
NEW ORLEANS — Patients with paroxysmal nocturnal hemoglobinuria who received iptacopan vs. standard therapy had clinically meaningful and significant improvement in symptoms, results of the phase 3 APPLY-PNH trial showed.
National registry may reduce mortality among alloimmunized people with sickle cell disease
A nationwide red blood cell alloantibody exchange could reduce mortality among alloimmunized individuals with sickle cell disease, according to study results presented at ASH Annual Meeting and Exposition.
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Headline News
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Headline News
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Headline News
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