Genitourinary Cancer News

Cigarette smoking appeared significantly associated with poor pathological response to cisplatin-based neoadjuvant chemotherapy among patients with muscle-invasive bladder cancer who underwent radical cystectomy, according to results of a single-center study.

The overall rate of cancer deaths in the U.S. has declined by 27% during the past 25 years, with approximately 2.6 million fewer cancer deaths reported between 1991 and 2016, according to data from Cancer Statistics 2019, American Cancer Society’s annual report on cancer rates and trends.

The FDA granted fast track designation to vofatamab for the treatment of advanced or metastatic urothelial cell carcinoma that harbors fibroblast growth factor receptor 3 mutation or fusion.

Vicinium induced clinically meaningful complete responses among patients with high-grade nonmuscle-invasive bladder cancer who were unresponsive to bacillus Calmette-Guérin, according to preliminary efficacy data from the ongoing phase 3 VISTA registration trial reported by the drug’s manufacturer.

Systemic lupus erythematosus is associated with an increased risk for 16 cancers, including Hodgkin’s and non-Hodgkin’s lymphoma, leukemia and multiple myeloma, but a decreased risk for prostate cancer and cutaneous melanoma, according to data published in Arthritis Research & Therapy.

The use of immune checkpoint inhibitors to treat various types of cancer appeared linked to severe, inflammatory cardiovascular immune-related adverse events soon after the start of treatment, according to an observational, retrospective, pharmacovigilance study published in The Lancet Oncology.

HIV-infected Hispanic adults in the United States demonstrated a higher risk for HPV-related cancers than Hispanics who did not have HIV, according to a study published in Cancer.

The NIH awarded a 5-year, $693,000 grant to The Feinstein Institute for Medical Research to develop and test a digital health platform to help young female cancer survivors evaluate their options for having children and plan for the future.

Older adults had a 69% higher risk for myocardial infarction and ischemic stroke in the year prior to cancer diagnosis, according to research published in Blood.

Rates of therapy-related myelodysplastic syndrome and acute myeloid leukemia have risen significantly in the modern era following chemotherapy for nearly all solid tumor cancer types, according to results of a population-based cohort study published in JAMA Oncology.