Genitourinary Cancer News

SAN FRANCISCO — Young men with metastatic testicular cancer who underwent cytotoxic chemotherapy experienced increases in body adipose mass with decreased muscle density, according to a retrospective study presented at Genitourinary Cancers Symposium.

Overall cancer death rates are dropping faster among black Americans than white Americans, according to a report published in CA: A Cancer Journal for Clinicians.

Patient sex had no statistically significant impact on the efficacy of immunotherapy for treatment of advanced cancers, according to a study published in JAMA Oncology.

SAN FRANCISCO — The combination of avelumab and axitinib induced longer PFS and higher objective response rates than sunitinib among previously untreated patients with advanced renal cell carcinoma, according to results from the ongoing phase 3 JAVELIN Renal 101 trial presented at Genitourinary Cancers Symposium.

Researchers in the United Kingdom have launched a 2-year trial to evaluate whether a breath test can be used for early detection of multiple cancer types.

SAN FRANCISCO — Adding adjuvant chemotherapy to postoperative radiotherapy improved DFS and OS among patients with locally advanced bladder cancer after radical cystectomy, according to results of a randomized phase 3 study presented at Genitourinary Cancers Symposium.

SAN FRANCISCO — Cabozantinib induced early tumor shrinkage — associated with prolonged OS — at a higher rate and to a greater degree than everolimus among patients with advanced renal cell carcinoma, according to data from the phase 3 METEOR study presented at Genitourinary Cancers Symposium.

SAN FRANCISCO — Malignant pheochromocytomas appeared to feature a variety of genomic alterations, some of which, including RET, NF1 and FGFR1, may be potential targets for therapy in the metastatic setting, according to results of a comprehensive genomic profiling study presented at Genitourinary Cancers Symposium.

SAN FRANCISCO — Retroperitoneal lymph node dissection conferred favorable survival rates among men with testicular seminoma used as first-line therapy or following chemotherapy, according to study results presented at Genitourinary Cancers Symposium.

SAN FRANCISCO — Characterization of genomic alterations in penile squamous cell carcinoma revealed involvement of multiple cancer genes that likely contribute to tumor development, as well as a genomic profile that appears similar to other HPV-related squamous cell carcinomas, according to study results presented at Genitourinary Cancers Symposium.