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Genitourinary Cancer News
Combination active in HER2-expressing urothelial carcinoma
SAN FRANCISCO — The combination of fam-trastuzumab deruxtecan-nxki and nivolumab demonstrated antitumor activity among patients with HER2-expressing urothelial carcinoma, according to results presented at ASCO Genitourinary Cancers Symposium.
AACR report: Pandemic led to nearly 10 million missed cancer screenings in 7 months
American Association for Cancer Research released a first-of-its-kind report detailing the impact of the COVID-19 pandemic on the cancer community, both in patient care and research practice.
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Patients with cancer have no added adverse reactions to COVID-19 vaccines
Patients with cancer had few differences in reported adverse events compared with people without cancer after receiving COVID-19 vaccines, according to study results published in JNCCN — Journal of the National Comprehensive Cancer Network.
Immunotherapy benefits older patients with cancer, but closer monitoring may be warranted
Older patients with cancer benefited from single-agent immune checkpoint inhibitors but had higher rates of adverse events and therapy discontinuation with increasing age, according to results of a retrospective study in JAMA Oncology.
Germline biomarkers predict adverse events from PD-1/PD-L1 checkpoint inhibitors
Germline microRNA-based biomarkers accurately predicted grade 2 or higher immune-related adverse events associated with anti-PD-1/PD-L1 therapy among patients with various cancer types, according to study results.
Trial-ineligible patients more likely to receive immunotherapy despite lack of benefit
Trial-ineligible patients with advanced cancer appeared nearly twice as likely as trial-eligible patients to receive immunotherapy, despite no evidence of a survival benefit compared with chemotherapy for this population.
Biden relaunches Moonshot with aim to cut cancer deaths by at least 50% in 25 years
President Joe Biden has unfinished business with cancer.
Dual checkpoint blockade shows promising activity in advanced cervical cancer
Balstilimab plus zalifrelimab demonstrated promising and durable activity among women with recurrent and/or metastatic cervical cancer who relapsed after platinum-based therapy, according to a phase 2 study in Journal of Clinical Oncology.
PSA testing rates rose after USPSTF revised prostate cancer screening guideline
PSA testing rates increased after the U.S. Preventive Services Task Force revised its guidance on prostate cancer screening in 2017, according to results of a large national cohort study in JAMA Oncology.
Rural residents more likely to express feelings of cancer fatalism, information overload
Residents of rural areas demonstrated higher levels of cancer fatalism and cancer information overload than urban residents, according to a study in Cancer Epidemiology, Biomarkers & Prevention.
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