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Genitourinary Cancer News
Treatment sequencing key as options increase for patients with urothelial cancer
Optimal sequencing of therapy for metastatic urothelial carcinoma will be crucial to extend patient survival, given the number of drug approvals over the past decade, according to a speaker at Chemotherapy Foundation Symposium.
Yeast platform enables production of anticancer agent in short supply
Scientists from Denmark and the United States have engineered a yeast commonly used in foods to produce the precursor molecules for the anticancer agent vinblastine, a drug that has been in shortage several times in recent years.
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Thromboembolism linked to shorter survival in metastatic renal cell carcinoma
Thromboembolism incidence appeared high among patients who received immunotherapy-based combinations for metastatic renal cell carcinoma, according to retrospective study results.
Off-the-shelf CAR-T produces complete remission in patient with advanced kidney cancer
Treatment with CTX130, a novel chimeric antigen receptor T-cell therapy, led to disease control in more than three quarters of patients with advanced clear cell renal cell carcinoma, results from a phase 1 trial showed.
Cell-based therapy fails to significantly improve outcomes in metastatic renal cell carcinoma
The addition of a cell-based immune primer to sunitinib exhibited activity among patients with metastatic renal cell carcinoma, according to randomized phase 2 study results.
Tivozanib confers long-term PFS benefit in advanced renal cell carcinoma
Tivozanib improved long-term PFS compared with sorafenib among patients with relapsed or refractory advanced renal cell carcinoma, according to study results.
Immunotherapy combination shrinks tumors in surgery-ineligible renal cell carcinoma
Most patients with renal cell carcinoma ineligible for surgery and ablation achieved tumor reduction after treatment with nivolumab plus ipilimumab, according to study results.
Trials for advanced renal cell carcinoma often use restrictive eligibility criteria
Many contemporary clinical trials for metastatic renal cell carcinoma incorporate restrictive eligibility criteria, according to study results.
Nicholas J. Vogelzang, MD, posthumously receives humanitarian award named in his honor
The Kidney Cancer Association posthumously presented Nicholas J. Vogelzang, MD, FACP, FASCO, with a new award named in his honor.
Artificial intelligence may help predict cardiotoxicity in renal cell carcinoma
Artificial intelligence models can help predict cardiotoxicity risk among patients with renal cell carcinoma treated with VEGF receptor inhibitors, according to study results.
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