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Gastrointestinal Cancer News
2-year data confirm benefit of nivolumab regimen for advanced gastric, esophageal cancers
The addition of nivolumab to chemotherapy showed durable benefit for treatment-naive patients with advanced gastric cancer, gastroesophageal junction cancer or esophageal adenocarcinoma, 2-year data from the CheckMate 649 study showed.
‘Broken’ system: Labels, guidelines include cancer drugs that failed confirmatory trials
Indications for which cancer drugs receive accelerated approval often remain on drug labeling after confirmatory trials show no improvement in the primary efficacy endpoint, results of a retrospective, observational study showed.
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Second COVID-19 vaccine dose equally effective in people with, without solid cancers
Patients with solid tumor cancers sustained similar COVID-19 antibody levels as individuals without cancer 6 months after the second dose of the mRNA COVID-19 vaccine, according to study results published in Cancer Discovery.
Colorectal cancer diagnoses dropped by 40% during pandemic
Amid lockdowns, many countries implemented a suspension of routine surveillance for colorectal cancer, resulting in fewer diagnoses in older patients with more complications, according to a presentation during UEG Week Virtual.
AI bests high-definition white light colonoscopy in adenoma detection
Artificial intelligence-based computer-aided polyp detection decreased adenoma miss rate and increased first-pass adenoma per colonoscopy detection, according to research published in Clinical Gastroenterology and Hepatology.
TCR T cells ‘poised to play a central role’ in cancer immunotherapy
The world of cancer cell therapy continues to evolve, and the next breakthrough may include T cells genetically modified to include T-cell receptors that recognize a wider array of tumor-associated antigens.
TCR T cells ‘poised to play a central role’ in cancer immunotherapy
The world of cancer cell therapy continues to evolve, and the next breakthrough may include T cells genetically modified to include T-cell receptors that recognize a wider array of tumor-associated antigens.
FDA approves Erbitux with Braftovi for colorectal cancer subset
The FDA approved cetuximab in combination with encorafenib for treatment of certain patients with colorectal cancer.
FDA grants fast track designation to acelarin for biliary tract cancer
The FDA granted fast track designation to acelarin for treatment of biliary tract cancer.
Pembrolizumab extends OS in pretreated hepatocellular carcinoma
Pembrolizumab prolonged OS compared with placebo for certain patients with advanced hepatocellular carcinoma, according to topline data released by the agent’s manufacturer.
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