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Gastrointestinal Cancer News
Real-time 3D imaging may improve efficacy of cancer radiotherapy
New 3D imaging technology developed at University of Michigan enables real-time measurement of radiation treatment, enhancing precision and potentially minimizing off-target effects.
Trilaciclib trial in colorectal cancer halted after early efficacy data favor placebo
A phase 3 trial of trilaciclib in combination FOLFOXIRI and bevacizumab for patients with metastatic colorectal cancer met its co-primary endpoints but will be terminated based on early efficacy data, according to the agent’s manufacturer.
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ODAC: Single-arm trial data will suffice for dostarlimab in rectal cancer subgroup
Data from a pair of single-arm clinical trials will be sufficient to illustrate the benefits and risks of dostarlimab-gxly for a subgroup of patients with rectal cancer, according to the FDA’s Oncologic Drugs Advisory Committee.
Septic shock linked to ‘surprisingly high’ mortality rate among patients with solid tumors
Among patients with solid tumors, septic shock was associated with a 69.4% 28-day mortality rate, according to a study published in CHEST.
BMI linked to safety of checkpoint inhibitors among patients with advanced cancer
High BMI appeared associated with increased risk for any-grade immune-related adverse events among a cohort of patients with advanced cancer undergoing treatment with immune checkpoint inhibitors.
VIDEO: Radiotherapy can mitigate pain in pancreatic, hepatic cancer
In a video interview, Benjamin Schlechter, MD, of Dana-Farber Cancer Institute, spoke about two presentations on using radiation palliatively presented at ASCO Gastrointestinal Cancers Symposium.
VIDEO: Data on drug combination impacts standard of care in refractory colorectal cancer
Benjamin Schlechter, MD, of Dana-Farber Cancer Institute, discussed the mature phase 3 data on the addition of bevacizumab to trifluridine/tipiracil in refractory colorectal cancer in a video interview with Healio.
VIDEO: Recent metastatic pancreatic cancer study ‘leaves us with many questions’
In a video interview, Benjamin Schlechter, MD, talked about a “fascinating, compelling and important study” that looked at liposomal irinotecan injection regimen vs. nab-paclitaxel and gemcitabine in metastatic pancreatic cancer.
Researchers explore connections between cancer and genetic ancestry
Researchers at Cold Spring Harbor Laboratory have developed software that correctly deduces continental ancestry from tumor DNA and RNA.
VIDEO: T-cell-directed therapy targeting HER2 under investigation for solid tumors
Benjamin Schlechter, MD, of Dana-Farber Cancer Institute, discussed a trial-in-progress investigating autologous T-cell antigen coupler T cells targeting HER2 in relapsed or refractory solid tumors in a video interview with Healio.
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