Gastrointestinal Cancer News

Researchers at UT Southwestern Medical Center have introduced a new metric that may be useful in predicting which patients are likely to develop immunotherapy toxicity.

VANCOUVER, British Columbia — Predictors of sessile serrated lesions among veterans who underwent colonoscopy within 12 months of a positive fecal immunochemical test included older age, obesity and smoking, according to a presenter.

The FDA approved pembrolizumab in combination with gemcitabine and cisplatin chemotherapy for adults with locally advanced unresectable or metastatic biliary tract cancer.

VANCOUVER, British Columbia — A next-generation, multitarget stool DNA test detected colorectal cancer with 94% sensitivity and 91% specificity, outperforming fecal immunochemical testing, according to late-breaking data here.

The FDA granted accelerated approval to entrectinib for infants aged 1 month and older who have solid tumors that harbor neurotrophic tyrosine receptor kinase, or NTRK, gene fusion for whom there are no effective treatments.

VANCOUVER, British Columbia — The “disproportionate density” of early-onset colorectal cancer mortality in the Southern United States is associated with high food insecurity and low access to healthy food, according to a presenter here.

VANCOUVER, British Columbia — The risk for colorectal cancer was lower among patients undergoing colonoscopy for diverticulitis compared with routine cancer screening, according to a presenter at the ACG Annual Scientific Meeting.

Researchers observed an inverse association between diabetes severity and survival outcomes among patients who underwent curative resection for colorectal cancer, according to study results.

MADRID — A novel T-cell engager appeared safe and exhibited efficacy as treatment for neuroendocrine tumors, according to study results presented at ESMO Congress.

MADRID — Sotorasib plus panitumumab prolonged PFS compared with standard of care for patients with chemorefractory KRAS G12C-mutated metastatic colorectal cancer, study results presented at ESMO Congress showed.