Gastrointestinal Cancer News

The FDA today authorized Integrated Mutation Profiling of Actionable Cancer Targets, or IMPACT, an in vitro diagnostic test that uses next-generation sequencing to rapidly identify the presence of mutations in 468 genes.

The quality of care received by older patients with colon cancer has significantly improved since 2001, but adherence to treatment guidelines could still be increased to further improve outcomes, according to new research published in Cancer.

With further guidance to test all cases of colorectal cancer for possible genetic markers, the FDA cleared the latest test to help distinguish between sporadic and genetic colorectal cancer, according to a release from Roche.

Elevated levels of insulin-like growth factor binding protein 3, or IGFBP3, were predictive of colorectal cancer among older men independent of both total IGF-I and conventional risk factors, study data show.

Genetic testing for mismatch repair deficiency in patients with colorectal cancer remains underused, especially in young adults, according to new research published in JAMA Oncology.

Stage at diagnosis appeared to be a major driver of racial and ethnic disparities in cancer survival, study data showed.

Women with locally advanced esophageal cancer who received chemoradiotherapy prior to surgery appeared more likely to achieve complete response and less likely to experience disease recurrence than their male counterparts, according to a frequency-matched nonrandomized retrospective review.

Although clinically effective, the use of regorafenib as second-line therapy for hepatocellular carcinoma did not appear cost-effective, according to study results.

A generic version of orally administered capecitabine returned less-than-anticipated cost savings over a 3-year span, according to study results published in JAMA Internal Medicine.

Alcohol use — whether light, moderate or heavy — increases cancer risk, and public health measures are needed to reduce high-risk alcohol consumption, according to an ASCO statement.