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Gastrointestinal Cancer News
‘Window of opportunity’ exists for durvalumab as pancreatic cancer maintenance therapy
A randomized clinical trial is underway to assess the efficacy of the novel immunotherapy durvalumab as maintenance therapy for patients with pancreatic cancer.
ACO enrollment associated with more appropriate breast, colorectal cancer screening
Enrolling in Medicare Shared Savings Program Accountable Care Organizations led to improvements in appropriateness of breast and colorectal cancer screening, according to findings published in JAMA Internal Medicine.
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Personalized colon cancer screening may be helpful in those without family history
Clinical risk factors may help guide colorectal cancer screening for average-risk individuals with no family history of the disease, according to new research publish in Gastrointestinal Endoscopy.
Tisch Cancer Institute appoints director of Center for Carcinoid and Neuroendocrine Tumors
Edward M. Wolin, MD, has been appointed director of the Center for Carcinoid and Neuroendocrine Tumors at Mount Sinai Health System’s Tisch Cancer Institute.
Study will compare fecal immunochemical tests with colonoscopy
A group of researchers at three sites in the United States have received a $4.5 million grant to determine the relative effectiveness of four fecal immunochemical tests for colorectal cancer screening compared with colonoscopy.
Exelixis submits FDA application for Cabometyx for advanced liver cancer
Exelixis submitted a supplemental new drug application to the FDA for Cabometyx tablets as a treatment for patients with previously treated advanced hepatocellular carcinoma based on positive results from a phase 3 trial, according to a press release.
Abnormal ALT after HBeAg seroclearance increases liver cancer risk
Patients with hepatitis B had a higher risk for hepatocellular carcinoma after HBV e antigen seroclearance if they were men, had higher levels of HBV DNA, were unable to achieve normalized alanine aminotransferase levels, and were older at the time of HBeAg seroclearance, according to a recently published study.
Radiotherapy with transarterial chemoembolization extends survival for certain patients with advanced hepatocellular carcinoma
A combination of transarterial chemoembolization and external beam radiotherapy prolonged PFS and OS among patients with advanced hepatocellular carcinoma with macroscopic vascular invasion, according to results of a randomized clinical trial.
Calcium supplements linked to precancerous colon polyps
Calcium supplements with or without vitamin D appeared to increase the risk for premalignant serrated polyps — specifically, sessile serrated adenomas and polyps — in patients with a history of colorectal adenomas, according to data from a recently completed chemoprevention trial.
Colonoscopy may be associated with appendicitis
Appendicitis occurred approximately seven times more frequently in the week following colonoscopy, according to study results from a large Veterans Administration cohort.
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